ID A0A0X8HRI6_9SACH Unreviewed; 1170 AA.
AC A0A0X8HRI6;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 22-FEB-2023, entry version 29.
DE RecName: Full=Condensin complex subunit 1 {ECO:0000256|PIRNR:PIRNR017127};
GN ORFNames=AW171_hschr31983 {ECO:0000313|EMBL:AMD20112.1};
OS Eremothecium sinecaudum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=45286 {ECO:0000313|EMBL:AMD20112.1, ECO:0000313|Proteomes:UP000243052};
RN [1] {ECO:0000313|EMBL:AMD20112.1, ECO:0000313|Proteomes:UP000243052}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58844 {ECO:0000313|EMBL:AMD20112.1,
RC ECO:0000313|Proteomes:UP000243052};
RA Dietrich F.S.;
RT "Genome sequence of the yeast Holleya sinecauda.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Regulatory subunit of the condensin complex, a complex
CC required for conversion of interphase chromatin into mitotic-like
CC condense chromosomes. The condensin complex probably introduces
CC positive supercoils into relaxed DNA in the presence of type I
CC topoisomerases and converts nicked DNA into positive knotted forms in
CC the presence of type II topoisomerases.
CC {ECO:0000256|PIRNR:PIRNR017127}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CND1 (condensin subunit 1) family.
CC {ECO:0000256|ARBA:ARBA00009606, ECO:0000256|PIRNR:PIRNR017127}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP014243; AMD20112.1; -; Genomic_DNA.
DR RefSeq; XP_017987108.1; XM_018131004.1.
DR AlphaFoldDB; A0A0X8HRI6; -.
DR STRING; 45286.A0A0X8HRI6; -.
DR GeneID; 28723346; -.
DR OrthoDB; 5480287at2759; -.
DR Proteomes; UP000243052; Chromosome iii.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007076; P:mitotic chromosome condensation; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR026971; CND1/NCAPD3.
DR InterPro; IPR032682; Cnd1_C.
DR InterPro; IPR007673; Condensin_cplx_su1.
DR InterPro; IPR024324; Condensin_cplx_su1_N.
DR PANTHER; PTHR14222; CONDENSIN; 1.
DR PANTHER; PTHR14222:SF2; CONDENSIN COMPLEX SUBUNIT 1; 1.
DR Pfam; PF12717; Cnd1; 1.
DR Pfam; PF12922; Cnd1_N; 1.
DR PIRSF; PIRSF017127; Condensin_D2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|PIRNR:PIRNR017127};
KW Cell division {ECO:0000256|ARBA:ARBA00022618,
KW ECO:0000256|PIRNR:PIRNR017127}; Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW DNA condensation {ECO:0000256|ARBA:ARBA00023067,
KW ECO:0000256|PIRNR:PIRNR017127};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776, ECO:0000256|PIRNR:PIRNR017127};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT DOMAIN 66..232
FT /note="Condensin complex subunit 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12922"
FT DOMAIN 986..1146
FT /note="Condensin complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12717"
FT REGION 453..515
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 859..884
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 458..501
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 859..878
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1170 AA; 132934 MW; 870B395370885CC1 CRC64;
MSFNLTEYLA RFRAIDKRSF PPVDNATREL NRITDRLAVS PEDIDSDQDL FETLIDLAQG
FSHLLPKLQQ QLSYLVSSCL RNLTQVIADN INDNSDREDI LSYIPSWKLH LEEFCYLLHV
ILTFLQDEIA SSSVSSAGKS NYRKNESTFT AEQFKRSCIQ VEGFLEVIVN VLELPLFKIF
QTTRTRDVFV GLFIKPLYVL IETEPVIKIQ SLKFFIMRII ASSVKNHGQL SNVLNLILSS
LTYFPHLANF NADLLKVLND DFGHPQLTEE ILRDISNKEF NTRDTTGPKV TSNFLIRLSE
ILPKVVLRQM TSIVKLLNNS SFTLRCAVVE ACGNIAVDII KDNEAIGNYK NQLEVLLELL
EERFRDSNPY VRSKAIQGCL KICELEIKFN RNRLNLVKLA VRSLQDRSSL VRRNAVKLLS
KLILTHPFTQ LHGTQLRLTE WEERHRAAMA HLKKSLSNNE RSSNRRSLHN KYDGSSERDS
SEDDSNSEEN SEHRADDGVE DYEVGPGNIE QLNERENITK GQDLLKMELT VRYYTEAVDF
ITAIHEGIKL ACGLLLSKNR NEVLETMDFF VLADAYDVEL SYLGIKRMLN LVWMEGSNNE
GITIASHLVE CYKNLFLTAP ETYNYKEKAI YIAKNLVNLT KNTSVADLAS LEKLLGMMYQ
AKFIDQNIVN VLWAIYNSAG NNQQETFTTE QIHGSIIIIG FLSLVDHEVA LKGIDALLNS
GLGEPGKKDS ILSKFTCIAL QRIVPADSKK SIDFEIPRAD DAVNKLQKKI LEYTDDPKYF
PVCEQAINAL FAISSQPDVV CTAVIKEKIM MTFGEPEDSA ESESHSRITS LTQLLFIVGQ
VAIKTIEYLE KCEAEFKKRK QERKVSNNDE KNQPEDGENN EMDVSINQDD ENNKELEMIG
GTVEDDFADA VQHIRENELI FGEFSLIGKF GPLVEEIVSN SGKFSDPALQ RSAVLCLEKL
MCVSSKYCER NLPLLITIME KSEDPIIRSN AVLGLGDMAV CFNNLVDENT DYLYHRLHDD
SIMVQRTCLM TVTFLILAGQ VKVKGQLAQM AKCLEDDDQG ISDMCKLFFT ELATKDNAIY
NGFIDIFSGL SNDDELKKES FKHIMKFLLS FIDKERQQKQ LSEKLLGRLS KVESQKQWDD
IAAVLNMLPY KNEKINLALE EGFKLVSARD
//
