ID   A0A0X8JUU7_9FUSO        Unreviewed;       449 AA.
AC   A0A0X8JUU7;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   RecName: Full=Permease IIC component {ECO:0000256|PIRNR:PIRNR006351};
GN   ORFNames=AXF11_06530 {ECO:0000313|EMBL:AMD95257.1};
OS   Leptotrichia sp. oral taxon 847.
OC   Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Leptotrichiaceae;
OC   Leptotrichia.
OX   NCBI_TaxID=1785996 {ECO:0000313|EMBL:AMD95257.1, ECO:0000313|Proteomes:UP000065271};
RN   [1] {ECO:0000313|Proteomes:UP000065271}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0260 {ECO:0000313|Proteomes:UP000065271};
RA   Holder M.E., Ajami N.J., Petrosino J.F.;
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The phosphoenolpyruvate-dependent sugar phosphotransferase
CC       system (PTS), a major carbohydrate active -transport system, catalyzes
CC       the phosphorylation of incoming sugar substrates concomitant with their
CC       translocation across the cell membrane.
CC       {ECO:0000256|PIRNR:PIRNR006351}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; CP014231; AMD95257.1; -; Genomic_DNA.
DR   RefSeq; WP_068156106.1; NZ_CP014231.1.
DR   AlphaFoldDB; A0A0X8JUU7; -.
DR   STRING; 1785996.AXF11_06530; -.
DR   KEGG; lot:AXF11_06530; -.
DR   OrthoDB; 1550290at2; -.
DR   Proteomes; UP000065271; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR   InterPro; IPR003352; PTS_EIIC.
DR   InterPro; IPR004501; PTS_EIIC_3.
DR   InterPro; IPR004796; PTS_IIC_cello.
DR   NCBIfam; TIGR00410; lacE; 1.
DR   PANTHER; PTHR33989; -; 1.
DR   PANTHER; PTHR33989:SF11; LICHENAN PERMEASE IIC COMPONENT; 1.
DR   Pfam; PF02378; PTS_EIIC; 1.
DR   PIRSF; PIRSF006351; PTS_EIIC-Cellobiose; 1.
DR   PROSITE; PS51105; PTS_EIIC_TYPE_3; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR006351};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR006351};
KW   Sugar transport {ECO:0000256|ARBA:ARBA00022597,
KW   ECO:0000256|PIRNR:PIRNR006351};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR006351}.
FT   TRANSMEM        21..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        65..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        158..180
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        201..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        242..262
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        303..323
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        335..354
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        360..379
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        412..430
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          4..429
FT                   /note="PTS EIIC type-3"
FT                   /evidence="ECO:0000259|PROSITE:PS51105"
SQ   SEQUENCE   449 AA;  49272 MW;  61E5A6DD8B4651DA CRC64;
     MINLEKLSMN MAKISEQRHL RAIRDGIVST LPLIIIGSIF LIIAIPPFPK DWAISILAKK
     HAAQILLPFR MTMFIMGLYA VIGIGYSLAK SYKLDGITGA ILSVCAFLLT LVPKVINPIE
     TITQTVGGKA VQVVVAEGTK GSQFLQEDLG YVMQMSNLGS AGLFVGIIAA IFAVEVYRFT
     TKTGFRIKMP DAVPESVARS FEALTPAAII IFTLTIITYW LKIDLHHIVG LIVTPFLKLS
     DSWFSVVVIV FLITFFWSFG IHGDSIIGSV VRPLWLMLLE QNATALANGK AIPHIAAEPL
     YQWFIWIGGS GTTIGLALLM LFKAKSSYGK ALGKAVILPA IFNINEPIIF GAPIMLNPTL
     LPPFIIVPIV NASITYFAMS MHWVNRVTST PPWTLPSPIG AFLATNGDFR AVILNIILIV
     ISIVIYYPFF TAYEKKLLVE EKAEKTGEE
//