ID A0A0Y9YBT3_PLABE Unreviewed; 447 AA.
AC A0A0Y9YBT3;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=26S protease regulatory subunit 4, putative {ECO:0000313|EMBL:CXI73750.1};
GN ORFNames=PBK173_000319800 {ECO:0000313|EMBL:CXI73750.1},
GN PBNK65E_000310500 {ECO:0000313|EMBL:SCN27110.1}, PBNK65NY_000309900
GN {ECO:0000313|EMBL:SCM24593.1}, PBSP11A_000310100
GN {ECO:0000313|EMBL:SCO63533.1}, PBSP11RLL_000310400
GN {ECO:0000313|EMBL:SCO61617.1};
OS Plasmodium berghei.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Vinckeia).
OX NCBI_TaxID=5821 {ECO:0000313|EMBL:CXI73750.1, ECO:0000313|Proteomes:UP000069549};
RN [1] {ECO:0000313|EMBL:CXI73750.1, ECO:0000313|Proteomes:UP000069549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K173 {ECO:0000313|EMBL:CXI73750.1,
RC ECO:0000313|Proteomes:UP000069549}, NK65 ny
RC {ECO:0000313|EMBL:SCM24593.1, ECO:0000313|Proteomes:UP000516480},
RC NK65e {ECO:0000313|EMBL:SCN27110.1,
RC ECO:0000313|Proteomes:UP000220214}, SP11 Antwerpcl1
RC {ECO:0000313|EMBL:SCO63533.1, ECO:0000313|Proteomes:UP000219860}, and
RC SP11 RLL {ECO:0000313|EMBL:SCO61617.1,
RC ECO:0000313|Proteomes:UP000219974};
RG Pathogen Informatics;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the AAA ATPase family.
CC {ECO:0000256|ARBA:ARBA00006914, ECO:0000256|RuleBase:RU003651}.
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DR EMBL; LT160032; CXI73750.1; -; Genomic_DNA.
DR EMBL; LT608148; SCM24593.1; -; Genomic_DNA.
DR EMBL; LT614638; SCN27110.1; -; Genomic_DNA.
DR EMBL; LT608276; SCO61617.1; -; Genomic_DNA.
DR EMBL; LT608260; SCO63533.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0Y9YBT3; -.
DR VEuPathDB; PlasmoDB:PBANKA_1206600; -.
DR OMA; QDDTDPM; -.
DR Proteomes; UP000069549; Chromosome 12.
DR Proteomes; UP000219860; Chromosome 12.
DR Proteomes; UP000219974; Chromosome 12.
DR Proteomes; UP000220214; Chromosome 12.
DR Proteomes; UP000516480; Chromosome 12.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd19502; RecA-like_PAN_like; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032501; Prot_ATP_ID_OB_2nd.
DR PANTHER; PTHR23073; 26S PROTEASOME REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR23073:SF24; 26S PROTEASOME REGULATORY SUBUNIT 4; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF16450; Prot_ATP_ID_OB_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU003651};
KW Hydrolase {ECO:0000313|EMBL:CXI73750.1};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU003651};
KW Protease {ECO:0000313|EMBL:CXI73750.1};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942}.
FT DOMAIN 225..364
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 1..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..40
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 447 AA; 49709 MW; FC2244FA2D14079B CRC64;
MGNAQGGMNN NPYGFLGKKD DKDKGKDKEK KKLESSPPSH IGKRKKKKKG ATGHSKLPTV
TPNTKCRLKL LKLERIKDYL LLEEEFITNQ EQIKTTDDKN YGKLKIDDLR GSPMSVGTLE
ELIDENHGII ATSVGPEYYV NILSFVDKDL LEPGCSVLLN NKTNSVVGIL LDEVDPLVSV
MKVEKAPLES YADIGGLESQ IQEIKEAVEL PLTHPELYED IGIKPPKGVI LYGPPGTGKT
LLAKAVANET SATFLRVVGS ELIQKYLGDG PKLVREMFKV AEDHAPSIVF IDEIDAVGTK
RYEATSGGER EIQRTMLELL NQLDGFDSRG DVKVIMATNR IDSLDPALIR PGRIDRKIQL
PNPDTKTKRR IFQIHTSKMT MSPDVDLEEF VMSKDELSGA DIKAICTEAG LLALRERRMK
ITQLDLRKAR DKALYQKKGN IPEGLYL
//
