ID A0A100I8R5_ASPNG Unreviewed; 770 AA.
AC A0A100I8R5;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Choline kinase {ECO:0000313|EMBL:GAQ36280.1};
GN ORFNames=ABL_01586 {ECO:0000313|EMBL:GAQ36280.1};
OS Aspergillus niger.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=5061 {ECO:0000313|EMBL:GAQ36280.1, ECO:0000313|Proteomes:UP000068243};
RN [1] {ECO:0000313|Proteomes:UP000068243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An76 {ECO:0000313|Proteomes:UP000068243};
RX PubMed=26893421; DOI=10.1128/genomeA.01700-15;
RA Gong W., Cheng Z., Zhang H., Liu L., Gao P., Wang L.;
RT "Draft genome sequence of Aspergillus niger strain An76.";
RL Genome Announc. 4:E0170015-E0170015(2016).
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- PATHWAY: Phospholipid metabolism. {ECO:0000256|ARBA:ARBA00025707}.
CC -!- SIMILARITY: Belongs to the choline/ethanolamine kinase family.
CC {ECO:0000256|ARBA:ARBA00038211}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAQ36280.1}.
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DR EMBL; BCMY01000002; GAQ36280.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A100I8R5; -.
DR VEuPathDB; FungiDB:An01g11150; -.
DR VEuPathDB; FungiDB:ASPNIDRAFT2_1102057; -.
DR VEuPathDB; FungiDB:ATCC64974_14550; -.
DR VEuPathDB; FungiDB:M747DRAFT_242474; -.
DR OMA; CEQVINW; -.
DR Proteomes; UP000068243; Unassembled WGS sequence.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05157; ETNK_euk; 1.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR007521; Choline_kin_N.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR22603; CHOLINE/ETHANOALAMINE KINASE; 1.
DR PANTHER; PTHR22603:SF93; RE24176P; 1.
DR Pfam; PF04428; Choline_kin_N; 1.
DR Pfam; PF01633; Choline_kinase; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|EMBL:GAQ36280.1};
KW Transferase {ECO:0000313|EMBL:GAQ36280.1}.
FT DOMAIN 208..281
FT /note="Choline kinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04428"
FT REGION 1..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 182..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..82
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 770 AA; 86071 MW; D576448BC7D48B40 CRC64;
MPSVTDQTGL SGLEFDGPQP ILGTGLNVSP QRHHHTNGHE SSAIGSEGNA FRHRVPAPKK
SAARLPTHQP ASLSSQTSSV ITEPAHRLEK DGMSKNGEED PQNSLFAQVY EWLQREKSKR
RSHKATNLAA MDGVASDGDD DDDDGASVLV ERPLSSGADA AMALDKLEKI LIQYATSRQG
TDSVHFARRS GRRRQYSKGL RRGSASESDF SDHEAAAPSV DAVLDNSKTL AYSGGGGTED
DDNENSVSAR RAKDKEAWAL FKSEILRLTH TMQLKGWRKL PMELAADIGV VRLSGALTNA
VYVVTPPQNI PVPKAEDGSY SLVPRKPPPK LLLRIYGPQV DHLIDRDNEL QILRRLGRKN
IGPKVLGIFN NGRFEEYFEA RPLTPKELRD PPTMKQIAKR MRELHDGIDL LVDEREGGPM
VFNNWDKWVD RCEQVINWLD KEIRSEHNKS KAASEAWRRR GFVCGVPWPF FRKAVEGYRK
WLLSSCGGME GIKRQLVFAH NDTQYGNLLR MEPSHESPLL RPENVHKQLV VIDFEYASAN
TPGIEFANHF TEWCYNYHDA ERPWACDTSR YPNPEQQHQF IEAYLSHRPG LREQASPSIT
PLMRGLSTNT SSLAPLNLDD GPDVDVSSRF DIEKAHEDST SAKIQFYARQ TRLWRVLNSA
QWVAWGIVQA KVPGMEEGIA ADEAAAKAQN GHHGTNGNGV HSDVTAEVNH STGTPPVDAD
VDEAEEFDYL AYAQDRAMFF WSDLLALKII REDELPESLV QVIKARMIDY
//
