ID A0A100IAS4_ASPNG Unreviewed; 344 AA.
AC A0A100IAS4;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Enoyl reductase (ER) domain-containing protein {ECO:0000259|SMART:SM00829};
GN ORFNames=ABL_02345 {ECO:0000313|EMBL:GAQ37846.1};
OS Aspergillus niger.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=5061 {ECO:0000313|EMBL:GAQ37846.1, ECO:0000313|Proteomes:UP000068243};
RN [1] {ECO:0000313|Proteomes:UP000068243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An76 {ECO:0000313|Proteomes:UP000068243};
RX PubMed=26893421; DOI=10.1128/genomeA.01700-15;
RA Gong W., Cheng Z., Zhang H., Liu L., Gao P., Wang L.;
RT "Draft genome sequence of Aspergillus niger strain An76.";
RL Genome Announc. 4:E0170015-E0170015(2016).
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00008072}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAQ37846.1}.
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DR EMBL; BCMY01000003; GAQ37846.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A100IAS4; -.
DR PaxDb; 5061-CADANGAP00004069; -.
DR VEuPathDB; FungiDB:An04g04480; -.
DR VEuPathDB; FungiDB:ASPNIDRAFT2_1167142; -.
DR VEuPathDB; FungiDB:ATCC64974_80060; -.
DR VEuPathDB; FungiDB:M747DRAFT_295854; -.
DR OMA; FAEYCIP; -.
DR Proteomes; UP000068243; Unassembled WGS sequence.
DR GO; GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; IEA:InterPro.
DR CDD; cd08249; enoyl_reductase_like; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR047122; Trans-enoyl_RdTase-like.
DR PANTHER; PTHR45348; HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG); 1.
DR PANTHER; PTHR45348:SF2; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 11..337
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 344 AA; 36505 MW; B4027060B3059D37 CRC64;
MQKALVITAP GSRDVVERPI PTVPDDCLLV KTASVALNPT DWKSADRKPP GQVIGNDYSG
VVEEVGKGVK KAFRKGDCVC GWVQGCNSNN PESGAFAEYC IPKADLQIAI PDRLSFEEAS
TLGLGTITVG QGLYQSLKLA PPDAPLAHPE LILIYGGSTA TGTLAIQYAK LSGYTVLTTC
SAQNFDLVKS LGADAVFDYK DANAVQAIKD YAQDNLKLVF DTVAVESSAK FCGEVISSKG
GDYSALLKVN VPRDDVRSLF TIGYTAFGED FDFGGGIIPA KPEDREFAGQ FMSKAATFLA
EGKVKPHPVK LGPRGLQGVL EGLQDMKDGK VSGKKLVYNV ADTP
//
