ID   A0A100IF51_ASPNG        Unreviewed;      1092 AA.
AC   A0A100IF51;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=DEAD box helicase involved in nonsense mediated decay {ECO:0000313|EMBL:GAQ39536.1};
GN   ORFNames=ABL_03185 {ECO:0000313|EMBL:GAQ39536.1};
OS   Aspergillus niger.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=5061 {ECO:0000313|EMBL:GAQ39536.1, ECO:0000313|Proteomes:UP000068243};
RN   [1] {ECO:0000313|Proteomes:UP000068243}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=An76 {ECO:0000313|Proteomes:UP000068243};
RX   PubMed=26893421; DOI=10.1128/genomeA.01700-15;
RA   Gong W., Cheng Z., Zhang H., Liu L., Gao P., Wang L.;
RT   "Draft genome sequence of Aspergillus niger strain An76.";
RL   Genome Announc. 4:E0170015-E0170015(2016).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAQ39536.1}.
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DR   EMBL; BCMY01000004; GAQ39536.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A100IF51; -.
DR   VEuPathDB; FungiDB:An07g03990; -.
DR   VEuPathDB; FungiDB:ASPNIDRAFT2_1211893; -.
DR   VEuPathDB; FungiDB:ATCC64974_46070; -.
DR   VEuPathDB; FungiDB:M747DRAFT_230386; -.
DR   OMA; EWIMVEA; -.
DR   Proteomes; UP000068243; Unassembled WGS sequence.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   CDD; cd18808; SF1_C_Upf1; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR045055; DNA2/NAM7-like.
DR   InterPro; IPR041679; DNA2/NAM7-like_C.
DR   InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR047187; SF1_C_Upf1.
DR   PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR   PANTHER; PTHR10887:SF341; NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF13086; AAA_11; 1.
DR   Pfam; PF13087; AAA_12; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000313|EMBL:GAQ39536.1};
KW   Helicase {ECO:0000313|EMBL:GAQ39536.1};
KW   Hydrolase {ECO:0000313|EMBL:GAQ39536.1};
KW   Nucleotide-binding {ECO:0000313|EMBL:GAQ39536.1}.
FT   DOMAIN          307..680
FT                   /note="DNA2/NAM7 helicase helicase"
FT                   /evidence="ECO:0000259|Pfam:PF13086"
FT   DOMAIN          696..879
FT                   /note="DNA2/NAM7 helicase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13087"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1047..1092
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1069..1083
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1092 AA;  123559 MW;  4E43A2AE916EFCD5 CRC64;
     MDSEDHHRPG TPRSDPRLSE RDMDTRLLVN KDIREYLAQP SIDFAEEWLK KPDIPSSDEI
     LGNFGSAENE YVELTPNNIT GPWNSTDEYL KAHYELLRED AISPLRDAVA YVRDDPKMTD
     TKLVSIYDKV YFIGITFAQR GLGIRIRFST RRAEKNIAWE YSKRLVSGSM VALSPADDAF
     QQKCIVAIVA ARPLEGVQKH PPEIDIFLAR PEDFEFDPQK EWIMVEAKDG YYESVRHTMA
     ALQKLKQEKF PLSEHICLLD PNVRAPDYVE QDPVLDIQSV ASETAEAAEG HRVDILKNWP
     REPNQAMDST QWQALHEMLT KRLSLIQGPP GTGKTYVSVI ALRILLSNVK QGDSPIILAS
     QTNHALDQLL RLVATFETSY IRVGSRSNDP EIKRRTLYCV RQNEPAVTVH GSVLGAARKE
     QKALTQAISR ILQPFNAENT NVPLPASLFV EYGLLTETQL DNLKKGAEGW TRPTDSEDTD
     PLVVWLGDKL VPFEVGYERE NFGFEEDEVD LEYEQLKELE AEQGIEEDDY EILKGQFINL
     QDGVCGCKIS CSETSAIENL KQKDLWKVRE EARGAIYDVL RKQLKTKMTE NLRQQVLLYS
     KNCENLLIGK WERDYHVLRT AKVIGMTATG LSKYRGLISS LRPKIVLIEE AAEAIEAPIV
     AACFDSLQHM ILVGDHQQLR GHCTVQELGG EPYNLGVSMF ERLVKNGMKY VMLNRQRRMA
     PEIRQLLEPI YGELNDHESV RKRPGVRGMG IIRSYFFTHI WPESRDSLAS KFNDMEAQMI
     TEFVVYLVQN GNTVRDITIL TFYNGQRKKL LTVLRHHPYL QGQYMKVVTV DSYQGEENEI
     VILSLVRSGE NDIGFLSIAN RVCVALSRAR RGFYMFGNAN SLAKQNQLWR DVLTLMANNK
     PPRRLGTQLP VTCVKHKRTT FIQGLSDWNK INGGCDCHCE GTLDCGHPCP IKCHSFSHEQ
     VECNDICNKR MACKHVCSKP CVISHICRCT CEVASQLDNL RLDHESQGST APLEGPSSYP
     EAVRHYQAFA SGGAKEHDAL LLKKATETAA AARPTPGTEE DEDLLLSETE VASSPQERDT
     TVPLSEENLM EI
//