ID   A0A100IG79_ASPNG        Unreviewed;       478 AA.
AC   A0A100IG79;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Aldehyde dehydrogenase {ECO:0000313|EMBL:GAQ40665.1};
GN   ORFNames=ABL_03742 {ECO:0000313|EMBL:GAQ40665.1};
OS   Aspergillus niger.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=5061 {ECO:0000313|EMBL:GAQ40665.1, ECO:0000313|Proteomes:UP000068243};
RN   [1] {ECO:0000313|Proteomes:UP000068243}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=An76 {ECO:0000313|Proteomes:UP000068243};
RX   PubMed=26893421; DOI=10.1128/genomeA.01700-15;
RA   Gong W., Cheng Z., Zhang H., Liu L., Gao P., Wang L.;
RT   "Draft genome sequence of Aspergillus niger strain An76.";
RL   Genome Announc. 4:E0170015-E0170015(2016).
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003345}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAQ40665.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BCMY01000005; GAQ40665.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A100IG79; -.
DR   PaxDb; 5061-CADANGAP00011862; -.
DR   VEuPathDB; FungiDB:An15g04100; -.
DR   VEuPathDB; FungiDB:ASPNIDRAFT2_1183611; -.
DR   VEuPathDB; FungiDB:ATCC64974_29700; -.
DR   VEuPathDB; FungiDB:M747DRAFT_299785; -.
DR   OMA; FYTIESF; -.
DR   Proteomes; UP000068243; Unassembled WGS sequence.
DR   GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   CDD; cd07105; ALDH_SaliADH; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   PANTHER; PTHR43353:SF6; CYTOPLASMIC ALDEHYDE DEHYDROGENASE (EUROFUNG); 1.
DR   PANTHER; PTHR43353; SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU003345}.
FT   DOMAIN          34..469
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   ACT_SITE        254
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ   SEQUENCE   478 AA;  51235 MW;  21D6928472FF6B54 CRC64;
     MVTTTAIPLI IHGKDILLSN NDRKHPITSK SAPHLKSFQG ATSDLAVQAV ESCASAFPSW
     SQTPPEERRR LLLNLARLLR EKSSTIQTLI KDEIHCTPLW SQLNVEIAAG IVEETASVIT
     DAISGTIPSS QGNTYALVMK KPLGVVLGIA PWNAPVILGL RSVIPVVAAG NTAILKGSEL
     SPQTHYFLAA LFREAGFPPG VVNFVLHRPQ DAAEIYECMI QHPAVKKCNF TGSTQVGRVI
     ASKAAMALKP VLLELGGKNP VVVLEDADLE QAADEIIAAG YLNNGQICMS TDLVYVVQSV
     AKELTKKILE RLHSEDRPHK VVSAAGQARL TQLVEDARSK GAVIHQARNP LAEDPLAFPA
     TVIEGVTEEM EFYTIESFGP VFGIIAVESA EQGLQMVKRS AYGLSSAVFT RDHFKALGMS
     ADIAVGAVHV NGGTVHDEPT LPHGGVGDSG YGRFGGKWGL NEFLQTQTVI LNRVRASL
//