ID A0A100IHX1_ASPNG Unreviewed; 705 AA.
AC A0A100IHX1;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Homeobox transcription factor {ECO:0000313|EMBL:GAQ41566.1};
GN ORFNames=ABL_04242 {ECO:0000313|EMBL:GAQ41566.1};
OS Aspergillus niger.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=5061 {ECO:0000313|EMBL:GAQ41566.1, ECO:0000313|Proteomes:UP000068243};
RN [1] {ECO:0000313|Proteomes:UP000068243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An76 {ECO:0000313|Proteomes:UP000068243};
RX PubMed=26893421; DOI=10.1128/genomeA.01700-15;
RA Gong W., Cheng Z., Zhang H., Liu L., Gao P., Wang L.;
RT "Draft genome sequence of Aspergillus niger strain An76.";
RL Genome Announc. 4:E0170015-E0170015(2016).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the engrailed homeobox family.
CC {ECO:0000256|ARBA:ARBA00010896}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAQ41566.1}.
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DR EMBL; BCMY01000006; GAQ41566.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A100IHX1; -.
DR PaxDb; 5061-CADANGAP00006452; -.
DR VEuPathDB; FungiDB:An08g02580; -.
DR VEuPathDB; FungiDB:ASPNIDRAFT2_1140228; -.
DR VEuPathDB; FungiDB:ATCC64974_104310; -.
DR VEuPathDB; FungiDB:M747DRAFT_316491; -.
DR OMA; MDYEEYA; -.
DR Proteomes; UP000068243; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR PANTHER; PTHR24341; HOMEOBOX PROTEIN ENGRAILED; 1.
DR PANTHER; PTHR24341:SF6; HOMEOBOX PROTEIN INVECTED-RELATED; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}.
FT DOMAIN 63..123
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 65..124
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 116..267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 287..324
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 375..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 120..176
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 177..192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 226..267
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..324
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 376..391
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..409
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 415..453
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 705 AA; 76993 MW; 1B9D45DD7D5895D7 CRC64;
MNYLHHPYAF TGHAAVPMEQ PVAFDPTMAH PSMMHPMDGY LYPHPPFDMV DFYHQPIMDY
EEYAENLSRP RLTKEQVETL EAQFQAHPKP SSNVKRQLAA QTNLSLPRVA NWFQNRRAKA
KQQKRQEEFE KMQKAKAEAE EAARGKSEST ESSDSKEDTK DSKEETDKDT PKQSVENTAE
RTKTPAASSS RPKHQKTRSE SAREATFASL QRALNAAVAA RDRYGQDGEN SQSPSMDGSV
SPTTTFSNNR CGSHDSSRHG QGDLSSSFSQ NAISWTSQSS QGALGYVTSG ESLTMPGMDG
TQHDAGHDSM QNVQFHPSQN EDWSHQLQTS KSLSGYRSAS DAEVSYNGVQ YPMQHDLSVP
RRGSSDELAD TLEGIGINTH PSSQLVNESD RSSWKEPSKE LDLAARRKRP RPAAIGTSRS
SSMLTGSSTM SPSTRLPSYG NSHGVRQSKS AQGLNTRYAG VRKASAAQRS PLNLSTFAEA
GALGSKADMS SMLQPAVTTG GLAPPTPLTP EDLHHLLPTT PSDGGYCLSA QPTSQLFPTT
QPMQINIASP PATPLAVDVL SSYPYQGVAP PMSAPAHYTS FADYASCEAP LTGRSWTDAT
SMPSPEASFQ SPCQLPQADL TTMSYDQAME QGPDHVPVTG SPSLMYHTSD VDMPTSAAFC
GDSKQTEFHI YEFPEQQEAH RFVAQQLPSQ KPKAYTFNNQ TPNDF
//
