ID A0A100IKZ7_ASPNG Unreviewed; 434 AA.
AC A0A100IKZ7;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Sucrase/ferredoxin-like family protein {ECO:0000313|EMBL:TPR10036.1};
DE SubName: Full=Vacuolar protein sorting-associated protein 4 {ECO:0000313|EMBL:GAQ43155.1};
GN ORFNames=ABL_05816 {ECO:0000313|EMBL:GAQ43155.1}, CAN33_0054460
GN {ECO:0000313|EMBL:TPR10036.1};
OS Aspergillus niger.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=5061 {ECO:0000313|EMBL:GAQ43155.1, ECO:0000313|Proteomes:UP000068243};
RN [1] {ECO:0000313|EMBL:GAQ43155.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An76 {ECO:0000313|EMBL:GAQ43155.1};
RA Wang L.S., Gao P.J., Liu L., Zhang H.Q., Cheng Z., Gong W.L.;
RT "Aspergillus niger An76 genome sequencing.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000068243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An76 {ECO:0000313|Proteomes:UP000068243};
RX PubMed=26893421; DOI=10.1128/genomeA.01700-15;
RA Gong W., Cheng Z., Zhang H., Liu L., Gao P., Wang L.;
RT "Draft genome sequence of Aspergillus niger strain An76.";
RL Genome Announc. 4:E0170015-E0170015(2016).
RN [3] {ECO:0000313|Proteomes:UP000197666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FDAARGOS_311 {ECO:0000313|Proteomes:UP000197666};
RA Kerrigan L., Tallon L., Sadzewicz L., Sengamalay N., Ott S., Godinez A.,
RA Nagaraj S., Vavikolanu K., Nadendla S., George J., Sichtig H.;
RT "FDA dAtabase for Regulatory Grade micrObial Sequences (FDA-ARGOS):
RT Supporting development and validation of Infectious Disease Dx tests.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:TPR10036.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FDAARGOS_311 {ECO:0000313|EMBL:TPR10036.1};
RA Kerrigan L., Tallon L.J., Sadzewicz L., Sengamalay N., Ott S., Godinez A.,
RA Nagaraj S., Vavikolanu K., Vyas G., Nadendla S., Aluvathingal J.,
RA Sichtig H.;
RT "FDA dAtabase for Regulatory Grade micrObial Sequences (FDA-ARGOS):
RT Supporting development and validation of Infectious Disease Dx tests.";
RL Submitted (FEB-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Endosome membrane
CC {ECO:0000256|ARBA:ARBA00004481}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004481}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the AAA ATPase family.
CC {ECO:0000256|ARBA:ARBA00006914, ECO:0000256|RuleBase:RU003651}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAQ43155.1}.
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DR EMBL; BCMY01000009; GAQ43155.1; -; Genomic_DNA.
DR EMBL; NKJJ02000008; TPR10036.1; -; Genomic_DNA.
DR PaxDb; 5061-CADANGAP00012531; -.
DR EnsemblFungi; CAK48610; CAK48610; An16g03010.
DR VEuPathDB; FungiDB:An16g03010; -.
DR VEuPathDB; FungiDB:ASPNIDRAFT2_1166087; -.
DR VEuPathDB; FungiDB:ATCC64974_70670; -.
DR VEuPathDB; FungiDB:M747DRAFT_130690; -.
DR eggNOG; KOG0739; Eukaryota.
DR OMA; IEWTNEF; -.
DR OrthoDB; 276256at2759; -.
DR Proteomes; UP000068243; Unassembled WGS sequence.
DR Proteomes; UP000197666; Unassembled WGS sequence.
DR GO; GO:1990621; C:ESCRT IV complex; IEA:EnsemblFungi.
DR GO; GO:0005886; C:plasma membrane; IEA:EnsemblFungi.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:EnsemblFungi.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:EnsemblFungi.
DR GO; GO:0097352; P:autophagosome maturation; IEA:EnsemblFungi.
DR GO; GO:0070676; P:intralumenal vesicle formation; IEA:EnsemblFungi.
DR GO; GO:0061764; P:late endosome to lysosome transport via multivesicular body sorting pathway; IEA:EnsemblFungi.
DR GO; GO:0032511; P:late endosome to vacuole transport via multivesicular body sorting pathway; IEA:EnsemblFungi.
DR GO; GO:0090148; P:membrane fission; IEA:EnsemblFungi.
DR GO; GO:0036258; P:multivesicular body assembly; IEA:EnsemblFungi.
DR GO; GO:0045053; P:protein retention in Golgi apparatus; IEA:EnsemblFungi.
DR GO; GO:0061709; P:reticulophagy; IEA:EnsemblFungi.
DR GO; GO:0016125; P:sterol metabolic process; IEA:EnsemblFungi.
DR CDD; cd02678; MIT_VPS4; 1.
DR CDD; cd19521; RecA-like_VPS4; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.58.80; Phosphotransferase system, lactose/cellobiose-type IIA subunit; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR007330; MIT_dom.
DR InterPro; IPR036181; MIT_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015415; Spast_Vps4_C.
DR InterPro; IPR045253; VPS4_MIT.
DR PANTHER; PTHR23074; AAA DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR23074:SF83; VESICLE-FUSING ATPASE; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF04212; MIT; 1.
DR Pfam; PF09336; Vps4_C; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00745; MIT; 1.
DR SUPFAM; SSF116846; MIT domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003651};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003651}.
FT DOMAIN 3..81
FT /note="MIT"
FT /evidence="ECO:0000259|SMART:SM00745"
FT DOMAIN 164..299
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 76..111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 411..434
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 434 AA; 47948 MW; 0F27FFF3F0AD47B5 CRC64;
MSNTDFLGRA IDTVKKAIEH DNEGEYEKAY QLYYSALELF MLALKWEKNP KSKEMIRAKA
GEYMDRAEKL KNHLATLDNR KKPSAVGANG KVAQGSGKGG NQDEDGEDAD SKKLRSALAG
AILSDKPNVQ WEDVAGLESA KEALKEAVIL PIKFPHLFTG KRQPWKGILL YGPPGTGKSY
LAKAVATEAN STFFSVSSSD LVSKWMGESE RLVKQLFNMA RENKPAIIFI DEVDALCGPR
GEGESEASRR IKTELLVQMD GVGKDSKGVL ILGATNIPWQ LDAAIRRRFQ RRVHISLPDI
NARMKMFMLA VGSTPCELTQ ADYRTLAEMS EGYSGSDISI AVQDALMQPI RKIQTATHYK
KVILDGAEKL TPCSPGDQGA MEMSWTTVEA DQLLEPPLVL KDFIKAVRNS RPTVSQEDLQ
RNSEWTKEFG SEGA
//
