ID A0A100ILE1_ASPNG Unreviewed; 447 AA.
AC A0A100ILE1;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Quinate transporter {ECO:0000256|ARBA:ARBA00043213};
GN ORFNames=ABL_06038 {ECO:0000313|EMBL:GAQ43377.1};
OS Aspergillus niger.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=5061 {ECO:0000313|EMBL:GAQ43377.1, ECO:0000313|Proteomes:UP000068243};
RN [1] {ECO:0000313|Proteomes:UP000068243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An76 {ECO:0000313|Proteomes:UP000068243};
RX PubMed=26893421; DOI=10.1128/genomeA.01700-15;
RA Gong W., Cheng Z., Zhang H., Liu L., Gao P., Wang L.;
RT "Draft genome sequence of Aspergillus niger strain An76.";
RL Genome Announc. 4:E0170015-E0170015(2016).
CC -!- FUNCTION: Integral membrane transporter that imports quinic acid to be
CC catabolized as a carbon source. {ECO:0000256|ARBA:ARBA00037560}.
CC -!- SUBUNIT: Interacts with creB. {ECO:0000256|ARBA:ARBA00038682}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004236}.
CC Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000256|ARBA:ARBA00010992}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAQ43377.1}.
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DR EMBL; BCMY01000009; GAQ43377.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A100ILE1; -.
DR VEuPathDB; FungiDB:An18g01700; -.
DR VEuPathDB; FungiDB:ASPNIDRAFT2_1147409; -.
DR VEuPathDB; FungiDB:ATCC64974_110460; -.
DR VEuPathDB; FungiDB:M747DRAFT_273257; -.
DR OMA; ERQCQIP; -.
DR Proteomes; UP000068243; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR GO; GO:0019630; P:quinate metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR003663; Sugar/inositol_transpt.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR PANTHER; PTHR48022:SF34; MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR48022; PLASTIDIC GLUCOSE TRANSPORTER 4; 1.
DR Pfam; PF00083; Sugar_tr; 1.
DR PRINTS; PR00171; SUGRTRNSPORT.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Quinate metabolism {ECO:0000256|ARBA:ARBA00022911};
KW Sugar transport {ECO:0000313|EMBL:GAQ43377.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000313|EMBL:GAQ43377.1}.
FT TRANSMEM 204..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 230..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 255..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 159..447
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 447 AA; 49517 MW; 30B891DCF2B96EB5 CRC64;
MKTAYPELGM LGGGGRNSSS NFDRASAAYL WLADTERLES LIRKSDAKRL CKERDDDGWL
ITRAGERQCQ IPLGQRLVPV WWRCGQAYMA SSIRSGDVIN FTTNDPEKLT LPSVDILWMQ
WKLTRALALC GAEEAPEDLY TDHNKVEGKE DVLVRQEEED EENERASAMY GYDSAFIGGT
LELPAFKTSL DIDGNNSTSL SSNVVSMFQA GAFFGAIFGF FFAEYFGRKP VILGSGVVFT
IGSGLQLVGR IDELYAGRVL TGLGVGASST MIPVYIAECS PALIRGRLVG CFEIMLQVAL
VFGFWVNYGV DKNIPSTTSA QWRIPVGIQM IPAGLLLICM SWMIESPRWL ASKNRIVQAQ
KNLAWVRNLP FDHPYVVNEL AEIQAAVNQE LEMSGGRRTL SHIVRECAAP GVRNRILIGV
MLMLLQNLTG INSINYYSPT IFRSVGY
//
