ID A0A100IM01_ASPNG Unreviewed; 838 AA.
AC A0A100IM01;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=DNA repair protein Pso2/Snm1 {ECO:0000313|EMBL:GAQ43679.1};
GN ORFNames=ABL_06340 {ECO:0000313|EMBL:GAQ43679.1};
OS Aspergillus niger.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=5061 {ECO:0000313|EMBL:GAQ43679.1, ECO:0000313|Proteomes:UP000068243};
RN [1] {ECO:0000313|Proteomes:UP000068243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An76 {ECO:0000313|Proteomes:UP000068243};
RX PubMed=26893421; DOI=10.1128/genomeA.01700-15;
RA Gong W., Cheng Z., Zhang H., Liu L., Gao P., Wang L.;
RT "Draft genome sequence of Aspergillus niger strain An76.";
RL Genome Announc. 4:E0170015-E0170015(2016).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA repair metallo-beta-lactamase (DRMBL)
CC family. {ECO:0000256|ARBA:ARBA00010304}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAQ43679.1}.
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DR EMBL; BCMY01000010; GAQ43679.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A100IM01; -.
DR VEuPathDB; FungiDB:An09g03490; -.
DR VEuPathDB; FungiDB:ASPNIDRAFT2_1148703; -.
DR VEuPathDB; FungiDB:ATCC64974_10200; -.
DR VEuPathDB; FungiDB:M747DRAFT_342817; -.
DR OMA; AQVHMHS; -.
DR Proteomes; UP000068243; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006974; P:DNA damage response; IEA:UniProtKB-KW.
DR CDD; cd16273; SNM1A-1C-like_MBL-fold; 1.
DR Gene3D; 3.40.50.12650; -; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR011084; DRMBL.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR23240:SF6; DNA CROSS-LINK REPAIR 1A PROTEIN; 1.
DR PANTHER; PTHR23240; DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED; 1.
DR Pfam; PF07522; DRMBL; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT DOMAIN 679..806
FT /note="DNA repair metallo-beta-lactamase"
FT /evidence="ECO:0000259|Pfam:PF07522"
FT REGION 1..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 95..243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 311..340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..34
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..69
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..158
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..176
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..214
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 311..332
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 838 AA; 91629 MW; 83D8BFF9934CF315 CRC64;
MPTPFPPRKP STPSRSTPAK SKATKRNTSL LSFFQKADGP PKATSRQSRI TQFATKAEKN
NTTGDEGSSG VRGGNGAAGA GGLFLEDAKK VVNFTSGGDY VREKTPEDIW EEEKEEERFQ
ENGGSVKKRR VEEGISLEDD IDNGSGEDKK KTESESGTES KSTQKPSRSV SGPFIDESDS
ESEDLEQFRE YENGTEIEAG VSDGKTNSAD ETQAPAVDVD TPPVREATSH DDDVYANFDD
LEEDECRGEE DFLDAFDDDE DFKGDIGLDD SGITGEDFGC EAPVCPVCQA VLTGLSETDV
SVHVNDCLDG KPTESLKHEP EAEPDPDPEP GPELKSSKGM SLADRAAIAR PAQRDPYASG
VAGTRSAFSK LMAGNAEDTA WNAAAANEVA SRGKQAYQRT CPFYKIIPGF SLCVDAFRYG
AVEGCNAYFL SHFHSDHYIG LTGSWRHGPI YCSRPTANLV CQQLKVDRKW LVPLEFEQKT
EIPGTGGAQV TLIEANHCPG SAIFLFEKSM GSGPSQRTHR VLHCGDFRAS PLHVQHALLR
PEITDPATGK ACQQRIDACY LDTTYLSPKY AFPGQEDVIE ACADLCVELD QDANDTNGRA
FGRPVNGKSG MLSKFVTAVT GSRPSPTQGS RPPGRLLVVI GTYSIGKERI CLGIARALKS
KIYATPAKQR VCACLEDAEL SSLLTDDPTE AQVHMQTLFE IRAETLADYL DSMKPHFTRV
VGFRPTGWTY RPPAGRMLDN PPVSVVLNSA HWKTPFSAKD LVPQRGSTRE SACFGVPYSE
HSSFRELSMF CCALRIGRVI PTVNVGSRKS RERMKAWIER WEAEKRKNGL YRVEGSHW
//
