ID A0A100IQ31_ASPNG Unreviewed; 234 AA.
AC A0A100IQ31;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 13-SEP-2023, entry version 20.
DE RecName: Full=GTP-binding nuclear protein {ECO:0000256|RuleBase:RU363057};
GN ORFNames=ABL_07962 {ECO:0000313|EMBL:GAQ45301.1};
OS Aspergillus niger.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=5061 {ECO:0000313|EMBL:GAQ45301.1, ECO:0000313|Proteomes:UP000068243};
RN [1] {ECO:0000313|Proteomes:UP000068243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An76 {ECO:0000313|Proteomes:UP000068243};
RX PubMed=26893421; DOI=10.1128/genomeA.01700-15;
RA Gong W., Cheng Z., Zhang H., Liu L., Gao P., Wang L.;
RT "Draft genome sequence of Aspergillus niger strain An76.";
RL Genome Announc. 4:E0170015-E0170015(2016).
CC -!- FUNCTION: GTP-binding protein involved in nucleocytoplasmic transport.
CC Required for the import of protein into the nucleus and also for RNA
CC export. Involved in chromatin condensation and control of cell cycle.
CC {ECO:0000256|RuleBase:RU363057}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU363057}.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Ran family.
CC {ECO:0000256|ARBA:ARBA00008028, ECO:0000256|RuleBase:RU363057}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAQ45301.1}.
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DR EMBL; BCMY01000015; GAQ45301.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A100IQ31; -.
DR VEuPathDB; FungiDB:An08g10060; -.
DR VEuPathDB; FungiDB:ASPNIDRAFT2_1148300; -.
DR VEuPathDB; FungiDB:ATCC64974_98710; -.
DR VEuPathDB; FungiDB:M747DRAFT_297094; -.
DR OMA; NACGVEN; -.
DR Proteomes; UP000068243; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd00877; Ran; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR002041; Ran_GTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR24071:SF0; GTP-BINDING NUCLEAR PROTEIN RAN; 1.
DR PANTHER; PTHR24071; RAN GTPASE; 1.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00627; GTPRANTC4.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00176; RAN; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51418; RAN; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|RuleBase:RU363057};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU363057};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU363057};
KW Protein transport {ECO:0000256|RuleBase:RU363057};
KW Transport {ECO:0000256|RuleBase:RU363057}.
SQ SEQUENCE 234 AA; 26557 MW; DF01FC82389A8E8F CRC64;
MAEQVPTFKL VLVGDGEKLH RPPNLTRHET SLLTGEISLQ TTFVKRHLTG EFEKKYIATL
GVEVHPLAFH TNLGNIQFDV WDTAGQEKFG GLRDGYYING QCGIIMFDVT SRITYKNVPN
WHRDLVRVCE GIPIVLCGNK VDVKERKVKA KTITFHRKKN LQYYDISAKS NYNFEKPFLW
LARKLVGNPQ LEFVAAPALA PPEVTVNKEL LAQYEQEMDA AANMPLPDEE DADL
//