ID A0A100VVJ6_9MYCO Unreviewed; 179 AA.
AC A0A100VVJ6;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Multisubunit Na+/H+ antiporter, MnhE subunit {ECO:0000313|EMBL:GAS86829.1};
GN ORFNames=RMCB_0925 {ECO:0000313|EMBL:GAS86829.1};
OS Mycolicibacterium brisbanense.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=146020 {ECO:0000313|EMBL:GAS86829.1, ECO:0000313|Proteomes:UP000069620};
RN [1] {ECO:0000313|EMBL:GAS86829.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM15654 {ECO:0000313|EMBL:GAS86829.1};
RA Katahira K., Ogura Y., Gotoh Y., Hayashi T.;
RT "Draft Genome Sequences of Five Rapidly Growing Mycobacterium Species, M.
RT thermoresistibile, M. fortuitum subsp. acetamidolyticum, M. canariasense,
RT M. brisbanense, and M. novocastrense.";
RL Genome Announc. 4:e00322-16(2016).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E
CC family. {ECO:0000256|ARBA:ARBA00006228}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAS86829.1}.
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DR EMBL; BCSX01000011; GAS86829.1; -; Genomic_DNA.
DR RefSeq; WP_062827835.1; NZ_JACKTM010000054.1.
DR AlphaFoldDB; A0A100VVJ6; -.
DR STRING; 146020.RMCB_0925; -.
DR OrthoDB; 3556991at2; -.
DR Proteomes; UP000069620; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR002758; Cation_antiport_E.
DR PANTHER; PTHR34584; NA(+)/H(+) ANTIPORTER SUBUNIT E1; 1.
DR PANTHER; PTHR34584:SF1; NA(+)_H(+) ANTIPORTER SUBUNIT E1; 1.
DR Pfam; PF01899; MNHE; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 31..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 63..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 179 AA; 20145 MW; C447C1F15F1CD7C6 CRC64;
MRHPLLRLWI LCFLILVWCL LWGHFSIANM VSGLVVALVI TLLLPLPAVP VEGRLHPLSL
LKLNVLVGYY LVLSSVQVAW LAIRPGPPPL VAVLRAHLAL KSDLVLALAV NIFNLIPGSI
VLEIDQSRRM LYLHVIDVGS ERSVHRFYRQ VEQVERMLIA AFERDEDWRP AAEQGVGRA
//
