ID A0A100VZI5_9MYCO Unreviewed; 515 AA.
AC A0A100VZI5;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 13-SEP-2023, entry version 36.
DE RecName: Full=Radical SAM core domain-containing protein {ECO:0000259|PROSITE:PS51918};
GN ORFNames=RMCB_2968 {ECO:0000313|EMBL:GAS88872.1};
OS Mycolicibacterium brisbanense.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=146020 {ECO:0000313|EMBL:GAS88872.1, ECO:0000313|Proteomes:UP000069620};
RN [1] {ECO:0000313|EMBL:GAS88872.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM15654 {ECO:0000313|EMBL:GAS88872.1};
RA Katahira K., Ogura Y., Gotoh Y., Hayashi T.;
RT "Draft Genome Sequences of Five Rapidly Growing Mycobacterium Species, M.
RT thermoresistibile, M. fortuitum subsp. acetamidolyticum, M. canariasense,
RT M. brisbanense, and M. novocastrense.";
RL Genome Announc. 4:e00322-16(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAS88872.1}.
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DR EMBL; BCSX01000024; GAS88872.1; -; Genomic_DNA.
DR RefSeq; WP_062829556.1; NZ_JACKTM010000010.1.
DR AlphaFoldDB; A0A100VZI5; -.
DR STRING; 146020.RMCB_2968; -.
DR Proteomes; UP000069620; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR034474; Methyltransferase_Class_D.
DR InterPro; IPR007197; rSAM.
DR PANTHER; PTHR43306; 7,8-DIHYDRO-6-HYDROXYMETHYLPTERIN DIMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43306:SF1; 7,8-DIHYDRO-6-HYDROXYMETHYLPTERIN DIMETHYLTRANSFERASE; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01100; methyltransferase_(Class_D); 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 104..327
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 515 AA; 57215 MW; BB0ABFE3559D4BA5 CRC64;
MGLRGDRLHR YVTAFCPHCH DEAPERPLTD VARLSGMLIE RDGRIWLERG CRSHGLVRTL
YDEDPEILSY LEEWTAPTKA HTPDTPGNFD PIPSAYLRGL PEMQTQHTCI LLEDIAETCN
LRCPTCFTDS SPDLRHVVPV ADVLANVDQR LARENGRLDV LMLSGGEPTL HPALPELLGE
LVSRPITRIL VNSNGVRIAN DDRLLDLLTT HRERVEVYLQ YDGLSEAAHR HHRGGDLRRT
KQQALQRLSE REIFTTLVMT AALGVNDDEI GAMVQLALDT PYVGGLTIQP QFGSGRSGRI
DPLERLTHTG VLKRLGPQTG DAVTWRDLTA LPCSHPHCCS VGYLVRDDAG QWRSLVSLIG
ADSLKDKLGL VANRIADTEI PRQLRLAVQE SLLGLLSEQS SLSHPQIGDV WRNICENCDL
GMSTLLTLAS SALPGRRRKI RQLLGERVVR LTVKPFMDMS TMIEERLVQC CVHVGTRSGS
ADQCAPFCAV QAWPALGRQR LSLSVGQELP LIEIR
//
