ID A0A100Y4C1_9ACTN Unreviewed; 293 AA.
AC A0A100Y4C1;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=GDSL family lipase {ECO:0000313|EMBL:KUH37465.1};
GN ORFNames=ATE80_18220 {ECO:0000313|EMBL:KUH37465.1};
OS Streptomyces kanasensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=936756 {ECO:0000313|EMBL:KUH37465.1, ECO:0000313|Proteomes:UP000054011};
RN [1] {ECO:0000313|EMBL:KUH37465.1, ECO:0000313|Proteomes:UP000054011}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ZX01 {ECO:0000313|EMBL:KUH37465.1,
RC ECO:0000313|Proteomes:UP000054011};
RA Zhang G., Han L., Feng J., Zhang X.;
RT "Genome-wide analysis reveals the secondary metabolome in Streptomyces
RT kanasensis ZX01.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUH37465.1}.
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DR EMBL; LNSV01000046; KUH37465.1; -; Genomic_DNA.
DR RefSeq; WP_058943286.1; NZ_LNSV01000046.1.
DR AlphaFoldDB; A0A100Y4C1; -.
DR STRING; 936756.ATE80_18220; -.
DR OrthoDB; 5503950at2; -.
DR Proteomes; UP000054011; Unassembled WGS sequence.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR CDD; cd01823; SEST_like; 1.
DR Gene3D; 3.40.50.1110; SGNH hydrolase; 1.
DR InterPro; IPR037460; SEST-like.
DR InterPro; IPR013830; SGNH_hydro.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR006311; TAT_signal.
DR PANTHER; PTHR37981; LIPASE 2; 1.
DR PANTHER; PTHR37981:SF1; SGNH_HYDRO DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13472; Lipase_GDSL_2; 1.
DR SUPFAM; SSF52266; SGNH hydrolase; 1.
DR PROSITE; PS51318; TAT; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR637460-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000054011};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..36
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 37..293
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007091216"
FT DOMAIN 46..283
FT /note="SGNH hydrolase-type esterase"
FT /evidence="ECO:0000259|Pfam:PF13472"
FT ACT_SITE 50
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-1"
FT ACT_SITE 275
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-1"
FT DISULFID 65..90
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-2"
FT DISULFID 138..151
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-2"
FT DISULFID 206..255
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-2"
SQ SEQUENCE 293 AA; 30074 MW; ED7CBAB430BFEC29 CRC64;
MRSVPPGRRA RTVLAATTTA AAALATAALG AGPAAGAETS VDRYVALGDS FASAAGVPDQ
VDSACMRSDR NYPALVRASL TPAAHRDVSC GGATTVHMTT AQNASAPPQF DALSADTDVV
TLTIGGNDIG FADIIVRCVS LGLFNPFGSP CKSSYTWTGT DQLAATVNAT APKIAAAIDG
VRQRAPHATI LVTGYPAILP DDGTNCPSVV SIAKGDAPWL RDTHKRLNAM IATQAAQRGA
VYVDTYTKSI GHDACKPAGT RWMEPLFTNA AAPFHPNAAG ERAMADAVLA ALR
//
