ID A0A100Y5K3_9ACTN Unreviewed; 822 AA.
AC A0A100Y5K3;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=ATE80_14710 {ECO:0000313|EMBL:KUH38104.1};
OS Streptomyces kanasensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=936756 {ECO:0000313|EMBL:KUH38104.1, ECO:0000313|Proteomes:UP000054011};
RN [1] {ECO:0000313|EMBL:KUH38104.1, ECO:0000313|Proteomes:UP000054011}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ZX01 {ECO:0000313|EMBL:KUH38104.1,
RC ECO:0000313|Proteomes:UP000054011};
RA Zhang G., Han L., Feng J., Zhang X.;
RT "Genome-wide analysis reveals the secondary metabolome in Streptomyces
RT kanasensis ZX01.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUH38104.1}.
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DR EMBL; LNSV01000032; KUH38104.1; -; Genomic_DNA.
DR RefSeq; WP_058942669.1; NZ_LNSV01000032.1.
DR AlphaFoldDB; A0A100Y5K3; -.
DR STRING; 936756.ATE80_14710; -.
DR OrthoDB; 7051771at2; -.
DR Proteomes; UP000054011; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054011};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..822
FT /note="SSD domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007091243"
FT TRANSMEM 255..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 305..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 353..375
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 381..407
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 446..466
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 605..624
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 636..656
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 676..697
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 718..737
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 275..404
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 111..196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 795..822
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 112..126
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..176
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 822 AA; 83013 MW; 9935BEB77CB468E9 CRC64;
MAAIARWCVR HRLVVVLLWL AAFGGAAAAT GVAGTAYSNE YEAPGTESGR ATAVLREAFP
GGGGDTATVV WHTDRGDVRS PVVTQRIAPM LDAVAALPGV AVVTSPYGPA GLPAPADGPP
PRAKAPGRPT AQSATTTGTA GATAAGTAAG ASGASTTGTG TATGGGTGTG TAAASATGAD
AATRDSGTPH GGISEDGRTA YATVTFDQRV EDVDAARADA LVDTARQAAG DGVRVEVGGS
VAALTGGGGG HTAEIVGVAV AAVVLFLAFG SLAASLLPIA TALVSVGTAA SGIALLGHVM
TVADFAPMLG MLIGLGVGID YALFIVTRHR KGLKRGLGVT EAAESAVATT GRAVVFAGAT
VCIALLGMLT LRLGFLNGVA IAASLTVVLT VVASVTLLPA LLSLIGMRAL SRRERRRLAE
HGPQPEPPTG FAARWSAFVE RHPKKLGAVA AVVMLVLALP TLSLRLGTSD QGNDPASATT
RQAYDLLAGG PDGDGFGPGV NGPLTLVAEL EGAGDRIAMN QLAARLPATP GVDSVGPVSY
SGSGNTAVVT VVPDSAPQSQ ETSDLVDRLR QDVLPTAEAG SSLDVHVGGV TAAYDDFAQV
VVGKLPLFVG VVITLGCLLL LLAFRSVGIP LKAAVMNVAA VASAFGVVVA VFQWGWGSEL
LGLGRAGPIE PFLPVIAVSV LFGLSMDYQV FLVSRMYEEW LETGDNRRAV RVGLAETSRV
INSAAVIMIA VFLAFVLSGD RVIAMFGIGL AAAVALDAFV LRTLLVPALM HLLGGANWWL
PRSLDRVLPR ISIEPPDPPE MPGPARVRIP GKRTSGDGEL VP
//
