ID A0A100Y9P0_9ACTN Unreviewed; 596 AA.
AC A0A100Y9P0;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Peptidase S8 {ECO:0000313|EMBL:KUH40234.1};
GN ORFNames=ATE80_02735 {ECO:0000313|EMBL:KUH40234.1};
OS Streptomyces kanasensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=936756 {ECO:0000313|EMBL:KUH40234.1, ECO:0000313|Proteomes:UP000054011};
RN [1] {ECO:0000313|EMBL:KUH40234.1, ECO:0000313|Proteomes:UP000054011}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ZX01 {ECO:0000313|EMBL:KUH40234.1,
RC ECO:0000313|Proteomes:UP000054011};
RA Zhang G., Han L., Feng J., Zhang X.;
RT "Genome-wide analysis reveals the secondary metabolome in Streptomyces
RT kanasensis ZX01.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240,
CC ECO:0000256|RuleBase:RU003355}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUH40234.1}.
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DR EMBL; LNSV01000004; KUH40234.1; -; Genomic_DNA.
DR RefSeq; WP_058940472.1; NZ_LNSV01000004.1.
DR AlphaFoldDB; A0A100Y9P0; -.
DR STRING; 936756.ATE80_02735; -.
DR OrthoDB; 9813435at2; -.
DR Proteomes; UP000054011; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR002884; P_dom.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023827; Peptidase_S8_Asp-AS.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR006311; TAT_signal.
DR PANTHER; PTHR43806:SF59; CEREVISIN-RELATED; 1.
DR PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR Pfam; PF01483; P_proprotein; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51829; P_HOMO_B; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00136; SUBTILASE_ASP; 1.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
DR PROSITE; PS51318; TAT; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000054011};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..596
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039405463"
FT DOMAIN 475..596
FT /note="P/Homo B"
FT /evidence="ECO:0000259|PROSITE:PS51829"
FT REGION 123..142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 174
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 214
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 410
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 596 AA; 60501 MW; F48785FEEDE630DE CRC64;
MLPHISAGLR RSAAAVALGA AVALAAPAAP AAAAPQAAAA TPTAATAPTG AWAAGTRAYL
VITTPGDTSA VRAAVAGNGG TVFAHYDAIG VVVAHSASAT FATTMRGVSG VQQVGATRTS
DVPADAYAPA LPPTPTQSAT TLTESDRWDM TQIRADQAWA VTTGSATVKV GVLDTGVDDL
HQDIAPNFNA ADSVSCAYGR ADTRAGAWRD VGTHGTHVAG TIAAAKNGKG VIGVAPGVRI
SSVRIAEPTT SMFFAENTIC GFMWAGDHGF RVTNNSYYTD PWMFNCPDDA DQAAIIEGVR
RAQAYAEGKG SLQVAAAGNS NYDLANKTTD TSSPNDSTPV SRRITNACVD IPTELPGVVT
VAAMGRGNVK ASYSNFGRDV IDIAAPGGDG SSGVYSTLPG GKYGNMNGTS MASPHVAGVA
ALLASVNPSF TPADLRARLA SQATDTACPS DSRCTGTTAK NGFFGEGQTD ALKAVGGSTP
TPGTYFENTA DVAITDNGTV ESPITVTGVS GNAPAALKVG VDVKHTYRGD LVLSLVAPDG
TVYPLEDFAN GDSGDDVVKT YTVNASAEVA AGTWKLRVRD VATQDSGRID AWNLTF
//
