ID A0A100YAT2_9ACTN Unreviewed; 287 AA.
AC A0A100YAT2;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=6-phosphogluconate dehydrogenase {ECO:0000313|EMBL:KUH40708.1};
GN ORFNames=ATE80_00540 {ECO:0000313|EMBL:KUH40708.1};
OS Streptomyces kanasensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=936756 {ECO:0000313|EMBL:KUH40708.1, ECO:0000313|Proteomes:UP000054011};
RN [1] {ECO:0000313|EMBL:KUH40708.1, ECO:0000313|Proteomes:UP000054011}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ZX01 {ECO:0000313|EMBL:KUH40708.1,
RC ECO:0000313|Proteomes:UP000054011};
RA Zhang G., Han L., Feng J., Zhang X.;
RT "Genome-wide analysis reveals the secondary metabolome in Streptomyces
RT kanasensis ZX01.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the HIBADH-related family.
CC {ECO:0000256|ARBA:ARBA00009080}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUH40708.1}.
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DR EMBL; LNSV01000001; KUH40708.1; -; Genomic_DNA.
DR RefSeq; WP_058940057.1; NZ_LNSV01000001.1.
DR AlphaFoldDB; A0A100YAT2; -.
DR STRING; 936756.ATE80_00540; -.
DR OrthoDB; 4029976at2; -.
DR Proteomes; UP000054011; Unassembled WGS sequence.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR048666; RedAm-like_C.
DR PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR PANTHER; PTHR43580:SF2; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR Pfam; PF21761; RedAm-like_C; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000054011}.
FT DOMAIN 8..153
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 160..285
FT /note="NADPH-dependent reductive aminase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21761"
SQ SEQUENCE 287 AA; 29012 MW; 52AFF6BDAC934D28 CRC64;
MTHIGTPVTV LGLGLMGGAL AEAFLRAGHP TTVWNRTRAK ADGLVARGAT LAESPAAALA
AAPLVVVCVS DYDAVADVLD GPLDGRVVVN LTSGTPSRAR ALAEEVARRG GGYLDGGIMA
VPEAVGTAAA VVAYSGPRPL YEAHESTLGS LGTGLHLGDD PGLSATHEMA TLVLMWGMLD
GFLNGAAILG TAGVSATAYL PVAQTAIDTV AGWLPGYARQ VDDGTYPADD GTVDTHLAAM
AHVVEESESL GVNAELPRLV KALAERAVTA GHGAGGYAAL VEQFRTP
//
