ID   A0A101CSH3_9FLAO        Unreviewed;       538 AA.
AC   A0A101CSH3;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=Alkaline phosphatase {ECO:0000313|EMBL:KUJ61572.1};
GN   ORFNames=AR687_11565 {ECO:0000313|EMBL:KUJ61572.1};
OS   Flavobacteriaceae bacterium CRH.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae.
OX   NCBI_TaxID=1742859 {ECO:0000313|EMBL:KUJ61572.1, ECO:0000313|Proteomes:UP000053826};
RN   [1] {ECO:0000313|EMBL:KUJ61572.1, ECO:0000313|Proteomes:UP000053826}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CRH {ECO:0000313|EMBL:KUJ61572.1,
RC   ECO:0000313|Proteomes:UP000053826};
RA   Newman J.D., Miller J.R., Jacobs K.T.;
RT   "Genome Sequence of Flavobacterium sp. CHR.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUJ61572.1}.
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DR   EMBL; LMAJ01000010; KUJ61572.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A101CSH3; -.
DR   STRING; 1742859.AR687_11565; -.
DR   OrthoDB; 9766127at2; -.
DR   Proteomes; UP000053826; Unassembled WGS sequence.
DR   GO; GO:0004035; F:alkaline phosphatase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd16016; AP-SPAP; 1.
DR   Gene3D; 3.30.1360.150; -; 1.
DR   Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR026263; Alkaline_phosphatase_prok.
DR   InterPro; IPR002591; Phosphodiest/P_Trfase.
DR   PANTHER; PTHR10151; ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE; 1.
DR   PANTHER; PTHR10151:SF126; PHOSPHODIESTERASE; 1.
DR   Pfam; PF01663; Phosphodiest; 1.
DR   PIRSF; PIRSF031924; Pi-irrepressible_AP; 1.
DR   SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|PIRNR:PIRNR031924};
KW   Phosphoprotein {ECO:0000256|PIRSR:PIRSR031924-50};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..538
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5007095258"
FT   ACT_SITE        72
FT                   /note="Phosphothreonine intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR031924-50"
FT   BINDING         93
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR031924-51"
FT   BINDING         155..157
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR031924-51"
SQ   SEQUENCE   538 AA;  60902 MW;  612A1E5B6555AEFE CRC64;
     MKKSIVLLTL FVISNLSAQQ RPKLVVGIVV DQMKMEYLYR FSDDFSPNGF KRLMNDGYTF
     QNMHYNYMPT YTAPGHASIY TGTTPSTHGI VGNEWFSRSL GKEMYCTDDA SVKTVGDGTA
     EEGAMSPKNL QATTITDEVR MGTNFAGKVI GMSLKDRGAI LPAGHFANWA FWYSKTGSFI
     SSTFYGEKLP EWVSQFNKEK HYMPYINKGW DLYKPASTYN ESLPDNNPYE GKLYGSSAPV
     FPYDLKTMYE KNDAGVLRAT PYGNDLLAEF AMKAIEKEEL GKDNITDFLT VSFSSTDYVG
     HLLGPRSMEL QDTYLRLDQT IADFLNYLDK TVGKDNYLLF LTADHAGAEN VIYLKDHKYN
     VDNYPSKDVK KSLQDFSIKT FGVDLVLNYS NFNIYFNKQI IKEKALELVK VKQAFKEFLI
     SQPQVKRVYT EEEILANSGN DYYLNFVAKG YDVTQDGDMI IIDKPGDIEY STTGTSHGTP
     YSYDTHVPAI FYGWHIKKGE SYDKKVITEI APTIAQKIKV AFPNGTEAKV LQEVLDEK
//