ID A0A101CVE6_9FLAO Unreviewed; 635 AA.
AC A0A101CVE6;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN ORFNames=AR687_06400 {ECO:0000313|EMBL:KUJ63018.1};
OS Flavobacteriaceae bacterium CRH.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae.
OX NCBI_TaxID=1742859 {ECO:0000313|EMBL:KUJ63018.1, ECO:0000313|Proteomes:UP000053826};
RN [1] {ECO:0000313|EMBL:KUJ63018.1, ECO:0000313|Proteomes:UP000053826}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CRH {ECO:0000313|EMBL:KUJ63018.1,
RC ECO:0000313|Proteomes:UP000053826};
RA Newman J.D., Miller J.R., Jacobs K.T.;
RT "Genome Sequence of Flavobacterium sp. CHR.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUJ63018.1}.
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DR EMBL; LMAJ01000004; KUJ63018.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A101CVE6; -.
DR STRING; 1742859.AR687_06400; -.
DR OrthoDB; 9778383at2; -.
DR Proteomes; UP000053826; Unassembled WGS sequence.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR CDD; cd05966; ACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR011904; Ac_CoA_lig.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:KUJ63018.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 12..68
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 70..462
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 519..598
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 635 AA; 71758 MW; AD464BFDE953CEF5 CRC64;
MSYYKIENLE QYFKHYNKSI REPRKFWGKI AEENFTWYQQ WDKVVDFNMA EAEVKWFTEA
KVNITKNCID RHLSKKGEKT AIIFEPNDPS ESALHITYNE LYERVSRMAN VLREQGVKKG
DRICIYLPMI PELAVAVLAC ARIGAIHSVI FAGFSASAVT ARINDCECKM VITSDGGYRG
NKTIDLKGIV DEALDTCPTV TKVLVVKRTQ NEVKMKDGRD VWLQPLLDAA IDNSVAEIMD
AEDPLFILYT SGSTGKPKGM VHTTAGYMVY TAYTFKNVFS HEENDIFWCT ADIGWITGHS
YILYGPLLNG GTTVIFEGVP SYPDFSRFWE IIEKHKITQF YTAPTAIRSL AKESLDYIQK
YPLKSLKVIG SVGEPINEEA WHWFNDHVGD KRCPVVDTWW QTETGGIMIS PIAFVTPTKP
TYATLPLPGI QPVLMDEKRN EIEGNQVVGS LCIKFPWPGI ARTIWGDHQR YKDTYFSSFP
GKYFTGDGAL RDEVGYYRIT GRVDDVVIVS GHNLGTAPIE DAINEHPAVA ESAIVGFPHD
IKGNALYGFV ILKETGEVRN KENLTREINQ YISDHIGPIA KLDKIQFVSG LPKTRSGKIM
RRILRKIAEG DFSNFGDTST LLNPEVVEDI MKERV
//
