ID A0A101HI45_9BACT Unreviewed; 999 AA.
AC A0A101HI45;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 13-SEP-2023, entry version 19.
DE SubName: Full=Anaerobic ribonucleoside-triphosphate reductase {ECO:0000313|EMBL:KUK77253.1};
DE Flags: Fragment;
GN ORFNames=XD93_0454 {ECO:0000313|EMBL:KUK77253.1};
OS candidate division WS6 bacterium 34_10.
OC Bacteria; Candidatus Dojkabacteria.
OX NCBI_TaxID=1641389 {ECO:0000313|EMBL:KUK77253.1, ECO:0000313|Proteomes:UP000053904};
RN [1] {ECO:0000313|Proteomes:UP000053904}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=26787827; DOI=10.1128/mbio.01669-15;
RA Hu P., Tom L., Singh A., Thomas B.C., Baker B.J., Piceno Y.M.,
RA Andersen G.L., Banfield J.F.;
RT "Genome-Resolved Metagenomic Analysis Reveals Roles for Candidate Phyla and
RT Other Microbial Community Members in Biogeochemical Transformations in Oil
RT Reservoirs.";
RL MBio 7:e01669-15(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUK77253.1}.
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DR EMBL; LGGO01000051; KUK77253.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A101HI45; -.
DR PATRIC; fig|1641389.3.peg.533; -.
DR Proteomes; UP000053904; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR GO; GO:0008998; F:ribonucleoside-triphosphate reductase activity; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR GO; GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
DR CDD; cd00081; Hint; 1.
DR Gene3D; 3.20.70.20; -; 2.
DR Gene3D; 2.170.16.10; Hedgehog/Intein (Hint) domain; 1.
DR Gene3D; 3.10.28.10; Homing endonucleases; 1.
DR InterPro; IPR005144; ATP-cone_dom.
DR InterPro; IPR003587; Hint_dom_N.
DR InterPro; IPR036844; Hint_dom_sf.
DR InterPro; IPR027434; Homing_endonucl.
DR InterPro; IPR004042; Intein_endonuc.
DR InterPro; IPR006141; Intein_N.
DR InterPro; IPR012833; NrdD.
DR NCBIfam; TIGR01445; intein_Nterm; 1.
DR PANTHER; PTHR21075; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR PANTHER; PTHR21075:SF0; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR Pfam; PF03477; ATP-cone; 1.
DR Pfam; PF14890; Intein_splicing; 1.
DR Pfam; PF13597; NRDD; 2.
DR SMART; SM00306; HintN; 2.
DR SUPFAM; SSF51294; Hedgehog/intein (Hint) domain; 2.
DR SUPFAM; SSF55608; Homing endonucleases; 1.
DR SUPFAM; SSF51998; PFL-like glycyl radical enzymes; 1.
DR PROSITE; PS51161; ATP_CONE; 1.
DR PROSITE; PS50819; INTEIN_ENDONUCLEASE; 2.
DR PROSITE; PS50817; INTEIN_N_TER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00492}; Autocatalytic cleavage {ECO:0000256|ARBA:ARBA00022813};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00492}; Protein splicing {ECO:0000256|ARBA:ARBA00023000}.
FT DOMAIN 10..107
FT /note="ATP-cone"
FT /evidence="ECO:0000259|PROSITE:PS51161"
FT DOMAIN 394..531
FT /note="DOD-type homing endonuclease"
FT /evidence="ECO:0000259|PROSITE:PS50819"
FT DOMAIN 851..991
FT /note="DOD-type homing endonuclease"
FT /evidence="ECO:0000259|PROSITE:PS50819"
FT NON_TER 999
FT /evidence="ECO:0000313|EMBL:KUK77253.1"
SQ SEQUENCE 999 AA; 114674 MW; B329EFCE6DE7EB74 CRC64;
MPAQKTAKMF KVKKRDGRIV KFEKERLVTG IFKAAESVGG KDRERANEIA DEVIKRLKEK
YSGKEYVTTK KIAAVTTQTL IDMGHGKTSV AFELFVDLKN QVKNIKSLID ADTLVRGYID
KVDWQVNENS NMAYSWQGLN NYISTTVQAN YWLHSIYPKE ISNANIDKDF HIHDLGMLAT
YCNGWSLEDL LLRGFTGVKG KIACAPPKHF STALGQAVNF LYTLQHEAAG AQAFSSFDTF
LAPFIRYDNL TYKQVKQKMQ EFLYNMNVPT RVGCQCVSED TQILTPKGWA TYKDIREGVT
IKTFNLKTGE IEDQKVESVF KGQHKGIMYN LKNRIQDQLI SPGHRVVRKL FNSDKYILEP
IEEVAKLKSP IIIPIAGNNT LKNRTNLPNE QLSLMAWIIS EGSVGKKGKH RSSHRVSIYQ
SKLKNRKNYD EIKNLLNHFG FKYSETTKSG LGKPVVRFRI NAEGSKTIHK WFGSKEDIKR
IPKDVLNLDL KKSRLFLNTY IKGDGYEGSK ISTTSLKILN ALQIVAVNAG YGFTVLTKEP
TLGKKKIYVL RLIKHKNTYI QEITKVKYDG VIWCPHTKNE TIIAKRNGKV FITGNTPFTN
ITMDLVPSGQ LAKQGVIIGG KIQKEKYKDF EKEMAMLNKA FCEIMMEGDA QGRLFSWPIP
TYNITKDFDW DNPKYKPVWE MTAKYGIPYF SNFINSDMNP DDARSMCLHP EEEIIYKEGG
NIKRANIGNL VENHRSGEYN KDGWVKIRKN EKLKALSLNL ESGKTEWTPI TRFLRIKDDE
LVTLTLEDGK EIRVSSKHLI PVLTEHGIEN KMAKDVNEKD YLLNLKQTNQ FNTKYQKISK
DIVLDEKVAK ILGYFVADGN YLKESRKNMK LYGEPRGLQF TFNSNTKENL EEIKKLLKDC
FNVSPKEKQD PRYNTYYLYV YDAKIARELK EVGFEKYGRL PNILFNSPKS VIEAFLDYHF
KGDGYEKRKE VHINDLELAR DLTLLYSLVG RPVTYKKGK
//
