ID A0A101HLA4_9BACT Unreviewed; 424 AA.
AC A0A101HLA4;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=Na+/H+ antiporter NhaD-like permease {ECO:0000313|EMBL:KUK78874.1};
GN ORFNames=XD94_1602 {ECO:0000313|EMBL:KUK78874.1};
OS Mesotoga prima.
OC Bacteria; Thermotogota; Thermotogae; Kosmotogales; Kosmotogaceae; Mesotoga.
OX NCBI_TaxID=1184387 {ECO:0000313|EMBL:KUK78874.1, ECO:0000313|Proteomes:UP000054092};
RN [1] {ECO:0000313|Proteomes:UP000054092}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=26787827; DOI=10.1128/mbio.01669-15;
RA Hu P., Tom L., Singh A., Thomas B.C., Baker B.J., Piceno Y.M.,
RA Andersen G.L., Banfield J.F.;
RT "Genome-Resolved Metagenomic Analysis Reveals Roles for Candidate Phyla and
RT Other Microbial Community Members in Biogeochemical Transformations in Oil
RT Reservoirs.";
RL MBio 7:e01669-15(2015).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CitM (TC 2.A.11) transporter family.
CC {ECO:0000256|ARBA:ARBA00009843}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUK78874.1}.
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DR EMBL; LGGP01000335; KUK78874.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A101HLA4; -.
DR PATRIC; fig|1184387.3.peg.2116; -.
DR Proteomes; UP000054092; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015105; F:arsenite transmembrane transporter activity; IEA:InterPro.
DR CDD; cd01116; P_permease; 1.
DR InterPro; IPR000802; Arsenical_pump_ArsB.
DR InterPro; IPR004680; Cit_transptr-like_dom.
DR PANTHER; PTHR43568; P PROTEIN; 1.
DR PANTHER; PTHR43568:SF1; P PROTEIN; 1.
DR Pfam; PF03600; CitMHS; 1.
DR PRINTS; PR00758; ARSENICPUMP.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 49..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 280..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 314..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..420
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 14..363
FT /note="Citrate transporter-like"
FT /evidence="ECO:0000259|Pfam:PF03600"
SQ SEQUENCE 424 AA; 45764 MW; 6405AE9A5EAD6075 CRC64;
MQWLFVLVVF VLAYILIISG KFNRSTVAFA AGIIILLSKV IPNFDMKEIG FLVDFNTIGI
LIGMMIVVGT LRTTGFFEFV AVHVVRISKG NVRALLVFFM VTIALFSAFL DNVTTILLFA
PIIFLVADSL EVSPRNFLLA GVLAANVGGT ATLIGDPPNI LVGSASGFGF MDFIRIDGPI
TLIALLITVV FLDRRVFKSY RLMGDKLQRL ASMDPNKAIV SKSSLYKSLT VFFGIIAGFL
LHDLIGVEPS LIALGGAAAA MILSGKSFSS LSEDIEWDTI FFFMGLFVLA SALQQVGITS
SISDLLGSLS GNRIILFLTL YWLSALMSGF IGAVPAVTFM IPVIEGMTAK YGVPMDVWWV
ISISACFGGS FSIAGAAANM VGVGLIEKHS REKLSYSDFL KFSMPLTIMT LAAGTAYILV
RFSF
//
