ID A0A101HLF0_9BACT Unreviewed; 746 AA.
AC A0A101HLF0;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=UvrABC system protein B {ECO:0000256|ARBA:ARBA00029504, ECO:0000256|RuleBase:RU003587};
GN ORFNames=XD95_0686 {ECO:0000313|EMBL:KUK78965.1};
OS Microgenomates bacterium 39_7.
OC Bacteria; Candidatus Microgenomates.
OX NCBI_TaxID=1641390 {ECO:0000313|EMBL:KUK78965.1, ECO:0000313|Proteomes:UP000054437};
RN [1] {ECO:0000313|Proteomes:UP000054437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=26787827; DOI=10.1128/mbio.01669-15;
RA Hu P., Tom L., Singh A., Thomas B.C., Baker B.J., Piceno Y.M.,
RA Andersen G.L., Banfield J.F.;
RT "Genome-Resolved Metagenomic Analysis Reveals Roles for Candidate Phyla and
RT Other Microbial Community Members in Biogeochemical Transformations in Oil
RT Reservoirs.";
RL MBio 7:e01669-15(2015).
CC -!- SUBUNIT: Forms a heterotetramer with UvrA during the search for
CC lesions. Interacts with UvrC in an incision complex.
CC {ECO:0000256|ARBA:ARBA00026033, ECO:0000256|RuleBase:RU003587}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|RuleBase:RU003587}.
CC -!- SIMILARITY: Belongs to the UvrB family. {ECO:0000256|ARBA:ARBA00008533,
CC ECO:0000256|RuleBase:RU003587}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUK78965.1}.
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DR EMBL; LGGQ01000086; KUK78965.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A101HLF0; -.
DR PATRIC; fig|1641390.4.peg.685; -.
DR Proteomes; UP000054437; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR CDD; cd17916; DEXHc_UvrB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001943; UVR_dom.
DR InterPro; IPR036876; UVR_dom_sf.
DR InterPro; IPR004807; UvrB.
DR InterPro; IPR041471; UvrB_inter.
DR InterPro; IPR024759; UvrB_YAD/RRR_dom.
DR PANTHER; PTHR24029; UVRABC SYSTEM PROTEIN B; 1.
DR PANTHER; PTHR24029:SF0; UVRABC SYSTEM PROTEIN B; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF04851; ResIII; 1.
DR Pfam; PF02151; UVR; 1.
DR Pfam; PF12344; UvrB; 1.
DR Pfam; PF17757; UvrB_inter; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF46600; C-terminal UvrC-binding domain of UvrB; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50151; UVR; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|RuleBase:RU003587};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769,
KW ECO:0000256|RuleBase:RU003587};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|RuleBase:RU003587};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881,
KW ECO:0000256|RuleBase:RU003587};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW SOS response {ECO:0000256|RuleBase:RU003587}.
FT DOMAIN 24..172
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 446..664
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 712..746
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
FT COILED 264..298
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 746 AA; 85785 MW; 17CED35BBF4C697C CRC64;
MKFQLKSNYQ PTGDQPEAIQ ALVAGLDQDR LHQTLLGVTG SGKTFTVANV IKQTQLPTLV
IAHNKTLAAQ LYQELRDFFP NNAVTYFVSY YDYYQPEAYI PSTDTYIEKE AQINDEIDKL
RLAATTNLLT RNDVIVVASV SCIYNLGNPV EYGQHIFEMI EGELIAQKTL LLQLANLQYQ
RSDIDFRRGT FRVRGDTIQV WPAYTDTALK IDTLENKIVK IQEIDPLSGA IITNPEEQQA
QTDYKGRYLL FPAKHYLIDP KTQENSLAQI KEDLKTQLEK LKKQNKQLEA YRLNKKVKYD
LEMIREFGFV NGIENYSRYF DGRSEGEPPF TLIDYFQENA RKFNSGTFLT VIDESHMTLP
QIRGMYFGDR SRKETLIEYG FRLPSALDNR PLTFDEFLEK TRHKLYVSAT PKDWEIKKSK
GRIVEQLVRP TGLLDPIVEL RSTESQIRDL IVEIVNRVAK GQRVLVTTLT KRMAEDLTDF
LNDEKKINKL LKQQQKQPKK SEKNITYLPV EQMKLGKMDK KYLTQAQIDE SLFDNENSLT
LPKVAYLHSE IETLDRSDIL DELRQGKFDV LVGINLLREG LDLPEVNLVA ILDADKTGFL
RSDTALIQTM GRAARHQEGR AILYADNLSK AMQDAISETQ RRRKTQEQYN QNHDITPTSI
QKPIREKLLK REKEEDLKAG DNPSSLIVQL SAKKQIDLAA IQADALTPQD KKSLSKKLVK
RMNQAAKELD YELAAILRDK IEEIQR
//
