ID A0A101HN00_9BACT Unreviewed; 472 AA.
AC A0A101HN00;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:KUK79846.1};
DE Flags: Fragment;
GN ORFNames=XD95_0060 {ECO:0000313|EMBL:KUK79846.1};
OS Microgenomates bacterium 39_7.
OC Bacteria; Candidatus Microgenomates.
OX NCBI_TaxID=1641390 {ECO:0000313|EMBL:KUK79846.1, ECO:0000313|Proteomes:UP000054437};
RN [1] {ECO:0000313|Proteomes:UP000054437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=26787827; DOI=10.1128/mbio.01669-15;
RA Hu P., Tom L., Singh A., Thomas B.C., Baker B.J., Piceno Y.M.,
RA Andersen G.L., Banfield J.F.;
RT "Genome-Resolved Metagenomic Analysis Reveals Roles for Candidate Phyla and
RT Other Microbial Community Members in Biogeochemical Transformations in Oil
RT Reservoirs.";
RL MBio 7:e01669-15(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUK79846.1}.
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DR EMBL; LGGQ01000004; KUK79846.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A101HN00; -.
DR Proteomes; UP000054437; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 29..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 124..196
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 232..456
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
FT NON_TER 472
FT /evidence="ECO:0000313|EMBL:KUK79846.1"
SQ SEQUENCE 472 AA; 53593 MW; A72331D2BA09CD7F CRC64;
MSNLFFCSSK RASVITDGYG LNQNRSRKIW ILSLIFLATM VTLLTRLAHL QLVQGAYYRQ
LADANRYFRQ VIPAERGVLL DRYHQLLVHN KKIYFQNKSD DLYPEKSRID HQRAMELMTE
ESWRVTYELR RQYLYPQELA HVLGYLAPVE AHELINNRQL KVRDWVGKLG LEQTLDQVLR
GQDGYQIFEI DTFGKKQRLI NELEAQSGHD IYTSLDPYLS RVAYQALGEM VGAVVVLDAD
TGQILSLIST PSFNSNDLGE SVLDEAREVA RQLAVRQYFQ DERKPFFNRA IGGVYPPGSV
FKMVTSIAGL EVDALDEHKT VLDEGILRVN EYEYANWLYT AQGATDGEIA LVRAIARSND
IYFYKAAEWI GPTNLARQAR ELGFGELTGV ELSGEAKGLV PDPAWKEEVI GERWFLGNTY
HFGIGQGDIA VTPIQVAQMV QALTKKGELC QPRLVVDDGK NAWSQKNCRN LG
//
