ID   A0A101JAE8_9ACTN        Unreviewed;       509 AA.
AC   A0A101JAE8;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Peptidase {ECO:0000313|EMBL:KUL23159.1};
GN   ORFNames=ADL15_46715 {ECO:0000313|EMBL:KUL23159.1};
OS   Actinoplanes awajinensis subsp. mycoplanecinus.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Actinoplanes.
OX   NCBI_TaxID=135947 {ECO:0000313|EMBL:KUL23159.1, ECO:0000313|Proteomes:UP000053244};
RN   [1] {ECO:0000313|EMBL:KUL23159.1, ECO:0000313|Proteomes:UP000053244}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL B-16712 {ECO:0000313|EMBL:KUL23159.1,
RC   ECO:0000313|Proteomes:UP000053244};
RA   Gilbert D.G.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUL23159.1}.
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DR   EMBL; LLZH01000333; KUL23159.1; -; Genomic_DNA.
DR   RefSeq; WP_067706566.1; NZ_LLZH01000333.1.
DR   AlphaFoldDB; A0A101JAE8; -.
DR   OrthoDB; 345880at2; -.
DR   Proteomes; UP000053244; Unassembled WGS sequence.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd09597; M4_TLP; 1.
DR   Gene3D; 3.10.170.10; -; 1.
DR   Gene3D; 3.10.450.40; -; 1.
DR   Gene3D; 1.10.390.10; Neutral Protease Domain 2; 1.
DR   InterPro; IPR011096; FTP_domain.
DR   InterPro; IPR027268; Peptidase_M4/M1_CTD_sf.
DR   InterPro; IPR001570; Peptidase_M4_C_domain.
DR   InterPro; IPR013856; Peptidase_M4_domain.
DR   PANTHER; PTHR33794; BACILLOLYSIN; 1.
DR   PANTHER; PTHR33794:SF1; BACILLOLYSIN; 1.
DR   Pfam; PF07504; FTP; 1.
DR   Pfam; PF01447; Peptidase_M4; 1.
DR   Pfam; PF02868; Peptidase_M4_C; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053244};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           30..509
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5007097545"
FT   DOMAIN          63..100
FT                   /note="FTP"
FT                   /evidence="ECO:0000259|Pfam:PF07504"
FT   DOMAIN          196..331
FT                   /note="Peptidase M4"
FT                   /evidence="ECO:0000259|Pfam:PF01447"
FT   DOMAIN          342..499
FT                   /note="Peptidase M4 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02868"
SQ   SEQUENCE   509 AA;  52018 MW;  6293CF726983D2E5 CRC64;
     MVRTPLSIAV AVGTVAASAL VGVSGPAAAQ PISPSVDAVA VADAVVAARP AALRAGAYDA
     FQRKQVYNSQ GLTYAAYDRT YKGLSVKGGD LVVVTDTAGA TRYTSVAQSS PIGELSTTPA
     VSQSAAIATA KKQFKTVTGV EATQLIVVAA EGQAAKLAYE TTVNGTSAEG VSRLTVDVDA
     ATGAVLSTHE NVTEATGTGT GWINGSVSLN TTLSGSTYSL KDPSTTNLSC QDAATNTVFS
     GTDNAWGNGV GTSKETGCVD ALYVAQKQKA MLSAWLGRNG QNGSGGAWPI RVGLNDQNAY
     YDGTQIQIGK NTAGKWISSL DVVGHELGHG IDDKTPGGIS KGGTQEFVAD TIGAATEAYA
     ANANDPFDYQ VGEEVNLVGS GPIRYMYNPS LAGDSNCYSS STPGSEVHAA AGPGNHWFYL
     LAQGSSGNGQ PASSTCNGTT VTGLGIQVAT KIMYNAMLLK TSSSSYAKYR VWTLQAAKNL
     YPGSCTNFNT VKAAWNAVSL PAQSGEPTC
//