ID A0A101JEK4_9ACTN Unreviewed; 876 AA.
AC A0A101JEK4;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Glycine/betaine ABC transporter permease {ECO:0000313|EMBL:KUL25350.1};
GN ORFNames=ADL12_35060 {ECO:0000313|EMBL:KUL25350.1};
OS Streptomyces regalis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=68262 {ECO:0000313|EMBL:KUL25350.1, ECO:0000313|Proteomes:UP000053923};
RN [1] {ECO:0000313|Proteomes:UP000053923}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 3151 {ECO:0000313|Proteomes:UP000053923};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363032};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363032}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. {ECO:0000256|RuleBase:RU363032}.
CC -!- SIMILARITY: In the C-terminal section; belongs to the OsmX family.
CC {ECO:0000256|ARBA:ARBA00035642}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the binding-protein-
CC dependent transport system permease family.
CC {ECO:0000256|ARBA:ARBA00035652}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUL25350.1}.
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DR EMBL; LLZG01000370; KUL25350.1; -; Genomic_DNA.
DR RefSeq; WP_062709957.1; NZ_LLZG01000370.1.
DR AlphaFoldDB; A0A101JEK4; -.
DR OrthoDB; 9787902at2; -.
DR Proteomes; UP000053923; Unassembled WGS sequence.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR CDD; cd13639; PBP2_OpuAC_like; 2.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; MetI-like; 1.
DR InterPro; IPR007210; ABC_Gly_betaine_transp_sub-bd.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR PANTHER; PTHR47737; GLYCINE BETAINE/PROLINE BETAINE TRANSPORT SYSTEM PERMEASE PROTEIN PROW; 1.
DR PANTHER; PTHR47737:SF1; GLYCINE BETAINE_PROLINE BETAINE TRANSPORT SYSTEM PERMEASE PROTEIN PROW; 1.
DR Pfam; PF00528; BPD_transp_1; 1.
DR Pfam; PF04069; OpuAC; 2.
DR SUPFAM; SSF161098; MetI-like; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 2.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363032};
KW Reference proteome {ECO:0000313|Proteomes:UP000053923};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363032};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363032};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363032}.
FT TRANSMEM 49..78
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 90..114
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 134..160
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 213..233
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 245..262
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT DOMAIN 87..266
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50928"
SQ SEQUENCE 876 AA; 94188 MW; 0294C4A62603C73E CRC64;
MPRIHFGDWI ETAVDWLQSH LTWVFDIVKA VLGGMYDGVD AVLGGGEPLL MAGILAVIAC
WLRGLLPGTL AFVGLALIDS LGLWDDAMDT LSLVLVAAVI TVVFAVPLGI WAARSNRVSA
QLRPVLDVMQ TMPAFIYLIP GVMFFGVGTT PGLLATIIFA MPPGVRMTEL GIRQVDGELI
EAAEAFGTSP RTTLARVQLP LALPTIMAGV NQVIMLALSM VVIGGMAGAG GLGEQVYSAI
TQLKVGLAAE SGVAVVVLAM YLDRMTGALG QRVSPLGRRA AAKAAVAAAG RFRLAHYKPG
GAVAVVGVVV LALVAGGMNQ AGSGGGEQTA AGNSTNVGQG EKINLGYIPW DEGTATTYLW
KELLEQRGYE TDVKQLDPGP LYSGVARGDI DFQTDAWLPT THKAYWDKYS SQLDDLGAWY
GPTSLELTVP SYVKGIDSLA DLKGQGKKFG GKIIGIEASA GMMGTLNKSV LKAYGLDGEY
KVVSSSTSSM LAELDRSIKK REPVVVTLWS PHWAYGKYDL KKLKDPEGAW GKGEQIHTVA
HKGFDKKNPT VAKWLKGFKL TETQLTSLEN DIRAAGEGQE QDGVRTWLKK NPGLVDKLAP
VAGGAKKQGR DAGRAVDIGY FPWDEAIAAT YLWQNILEDR GYKPNVEQLD PGPLYTSLAQ
GQMDVQLDGW LPTTHKEYVD RFKGQLDDLG AWYGPTSLEL TVPSYVKGVD SLADLKGRGE
EFGGKIIGIE ASAGMMGTLN KSVLKAYGLD GEYKVVSSST SSMLAELDRS IKKREPVVVT
LWSPHWAYGK YDLKKLKDPE GAWGQGEQIH TVAKKGFGRE FPELNGWLKN FKLTEEQLAS
LEVEIQKGGA GNEKESARRW MDTRPGIEDK LAPVTG
//
