ID A0A101JG47_9ACTN Unreviewed; 809 AA.
AC A0A101JG47;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=Aminoglycoside phosphotransferase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=ADL15_38880 {ECO:0000313|EMBL:KUL26178.1};
OS Actinoplanes awajinensis subsp. mycoplanecinus.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=135947 {ECO:0000313|EMBL:KUL26178.1, ECO:0000313|Proteomes:UP000053244};
RN [1] {ECO:0000313|EMBL:KUL26178.1, ECO:0000313|Proteomes:UP000053244}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL B-16712 {ECO:0000313|EMBL:KUL26178.1,
RC ECO:0000313|Proteomes:UP000053244};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUL26178.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LLZH01000308; KUL26178.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A101JG47; -.
DR OrthoDB; 30633at2; -.
DR Proteomes; UP000053244; Unassembled WGS sequence.
DR GO; GO:0018580; F:nitronate monooxygenase activity; IEA:InterPro.
DR CDD; cd04730; NPD_like; 1.
DR Gene3D; 3.90.1200.10; -; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 2.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002575; Aminoglycoside_PTrfase.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR004136; NMO.
DR PANTHER; PTHR32332; 2-NITROPROPANE DIOXYGENASE; 1.
DR PANTHER; PTHR32332:SF31; 2-NITROPROPANE DIOXYGENASE FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G09850)-RELATED; 1.
DR Pfam; PF01636; APH; 1.
DR Pfam; PF03060; NMO; 1.
DR SUPFAM; SSF51412; Inosine monophosphate dehydrogenase (IMPDH); 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053244}.
FT DOMAIN 174..399
FT /note="Nitronate monooxygenase"
FT /evidence="ECO:0000259|Pfam:PF03060"
FT DOMAIN 445..740
FT /note="Aminoglycoside phosphotransferase"
FT /evidence="ECO:0000259|Pfam:PF01636"
FT REGION 70..157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 343..365
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..149
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 809 AA; 85616 MW; 4D708BD2815336E0 CRC64;
MALTTAFTEL LGVRHPIALA PMGGSAGGAL AAAVSAGGGL GLLGAGDHAW LDRELPILTT
ALHHNADTAG LRDSRAPAGA QPPSGAHLPT DAPAPSDARP FPDTRFFPDT RAPSDTRAPS
DTRAPSDTRA PSDTRAPSDT PSDTRAPSDT RAPSGAPAPW GAGFLTWAIE PGLVERVLEH
GARAVMFSFG DPAPWVRMVH AAGALVIVQV TDLDEARQAV ELGADVIVAQ GTEAGGHGAR
RGRSVLSFVP LVVDLAGPTP VLAAGGIGDG RGLAAALALG ADGALLGTRF QATPESLAHP
MITAALLAGR GADTERSSVL DVVRGSAWSP KYTARTLAHP HLDRWRDREP EAAASTQAQQ
DYRDDVERGV IPPLPVWAGE AVDLITELVP AAGLVESLSL EAEQSLSRAG ARPPRASEAD
RFPPLPGRVQ AEIAECFRLG LVAECQAAPA GVMNLNWRLS TGNGQFAVKR LTDRSPEAFR
AAQDLLPRLA EAGFPVPAPL RTASGDTLQK INGFWYAVST WLPGTHPAGA DLDLGACTAL
GDLIGRLHLA LADLCPPAPR SLPDVPPDAA QARAELARYA QISADHASRS LNLGAGTTNQ
ALKLGTDTTN QALKLGTDTT NQALKLGTDT NQALKLGTDT TNRALEFGAE IARRRELLDR
VADQRPPDQD VSPCGWTHGD LQPFNLLAEN GLVTGILDWD RLDVRPYGLE VMRTATIMFS
DGGRTALDLD RTAAFIRGYR AQIPITSGQL VDAAERRWWT LATETWQLQR HYDAGDTSCD
HLFLTRGTFL HWWTSHRQQV QKTLSAVNH
//
