ID A0A101JN10_9ACTN Unreviewed; 551 AA.
AC A0A101JN10;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Trypsin {ECO:0000313|EMBL:KUL29523.1};
GN ORFNames=ADL15_27495 {ECO:0000313|EMBL:KUL29523.1};
OS Actinoplanes awajinensis subsp. mycoplanecinus.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=135947 {ECO:0000313|EMBL:KUL29523.1, ECO:0000313|Proteomes:UP000053244};
RN [1] {ECO:0000313|EMBL:KUL29523.1, ECO:0000313|Proteomes:UP000053244}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL B-16712 {ECO:0000313|EMBL:KUL29523.1,
RC ECO:0000313|Proteomes:UP000053244};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S1C family.
CC {ECO:0000256|ARBA:ARBA00010541}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUL29523.1}.
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DR EMBL; LLZH01000278; KUL29523.1; -; Genomic_DNA.
DR RefSeq; WP_067697231.1; NZ_LLZH01000278.1.
DR AlphaFoldDB; A0A101JN10; -.
DR OrthoDB; 9788136at2; -.
DR Proteomes; UP000053244; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd00987; PDZ_serine_protease; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001940; Peptidase_S1C.
DR PANTHER; PTHR43343; PEPTIDASE S12; 1.
DR PANTHER; PTHR43343:SF3; PROTEASE DO-LIKE 8, CHLOROPLASTIC; 1.
DR Pfam; PF13180; PDZ_2; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053244};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 193..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 451..538
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 1..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 143..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 363..408
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..74
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..97
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 98..112
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 372..408
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 551 AA; 55405 MW; A5893E3A8105A00B CRC64;
MNENETNPRP ADAGAEFSST ERVESEQPTA AQPPVASQPA AHQSAAPTSG AHPTPPQYDA
QPTAHHSPQL LHDAQPTAPS AWAQPAAHQQ SADPQSYQPA APQPPHAPAS PWQQPAPVSA
IPVTSQPYAA GYSPYAAQQQ PGYAQTGYGQ PAGYQHTGAW QHGATPTPPE GVVPVWAQGP
GAQPPRSGRG RKILMAGAAA IVIALLSGGV GAATVMAMDD NGSNPTVQTG NSSVTRVVDR
SSLAQIAAAV QDSVVSITTG SGEGSGVVMS ADGYIVTNNH VVASASGDTV NIIFADGKKA
TAKIVGTDPR TDLAVVKADG VSGLKAATFG DSSKMEVGDT VLALGSPLGL EGSVTAGIIS
AKDRTIESSS EEDQQEQQNP LGQSQQQQQQ PSTSTTMTGL LQTDAPINPG NSGGALVNTN
GEVIGINSAI ATSGSSSGNI GLGFSIPSNK AVDVAKALMA GTKVSHPALG VSVTTAENGG
ALVSQVTSGS AAAKAGLQQG DVITKVDGKE ISESDDLVAA VQAGSVGQQM NITFTRNGAE
KSVTVTLAES K
//
