ID   A0A101NCE3_9ACTN        Unreviewed;       397 AA.
AC   A0A101NCE3;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=ROK family transcriptional regulator {ECO:0000313|EMBL:KUM90570.1};
GN   ORFNames=AQI94_01840 {ECO:0000313|EMBL:KUM90570.1};
OS   Streptomyces pseudovenezuelae.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
OX   NCBI_TaxID=67350 {ECO:0000313|EMBL:KUM90570.1, ECO:0000313|Proteomes:UP000053039};
RN   [1] {ECO:0000313|EMBL:KUM90570.1, ECO:0000313|Proteomes:UP000053039}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40212 {ECO:0000313|EMBL:KUM90570.1,
RC   ECO:0000313|Proteomes:UP000053039};
RA   Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT   "Draft genome sequence of Streptomyces pseudovenezuelae DSM 40212, type
RT   strain for the species Streptomyces pseudovenezuelae.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC       {ECO:0000256|ARBA:ARBA00006479}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUM90570.1}.
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DR   EMBL; LMWM01000003; KUM90570.1; -; Genomic_DNA.
DR   RefSeq; WP_031048523.1; NZ_KQ948144.1.
DR   AlphaFoldDB; A0A101NCE3; -.
DR   OrthoDB; 3523179at2; -.
DR   Proteomes; UP000053039; Unassembled WGS sequence.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd00090; HTH_ARSR; 1.
DR   CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR   Gene3D; 3.30.420.40; -; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR011991; ArsR-like_HTH.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR000835; HTH_MarR-typ.
DR   InterPro; IPR000600; ROK.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR18964:SF149; BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE; 1.
DR   PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR   Pfam; PF12802; MarR_2; 1.
DR   Pfam; PF00480; ROK; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   3: Inferred from homology;
FT   DOMAIN          15..55
FT                   /note="HTH marR-type"
FT                   /evidence="ECO:0000259|Pfam:PF12802"
SQ   SEQUENCE   397 AA;  41245 MW;  183A44E1B805256D CRC64;
     MAGTPRTLRA MNDRAALDLL LEHGPLSRTR IGKLTGLSKP TASQLLARLE ASGLVLATGT
     SEGRPGPNAQ LYEVDPSAAY AAGLDVTPER VLAAVADITG RTVGSFELPT PGRRPAQPVV
     RQVTDALDGA VKAAGLARAD VHRLVIGTPG AFDPGTGRLR YASHLPGWHT PTLLDEIAAA
     LPMPVEYEND VNLVAVAEQR LGAARGHEDF VLLWNEGGLG AALVLGGRLH RGWTGGAGEV
     GFLPVPGAPL VRQVTKANSG GYQELAGSQA IPGLARELGM TDIPSGPYAE VAAALVERAA
     TEDTVLHRLL LETYATRLAT GLASLVSVLD PELVVLSGAS LTAGGDTLRA LVQAELEELA
     ASRPRLVVGA VHEHPVLRGA LESALAATRD EVFDTSR
//