ID A0A101NGJ3_9ACTN Unreviewed; 385 AA.
AC A0A101NGJ3;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:KUM92551.1};
GN ORFNames=AQI88_31930 {ECO:0000313|EMBL:KUM92551.1};
OS Streptomyces cellostaticus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=67285 {ECO:0000313|EMBL:KUM92551.1, ECO:0000313|Proteomes:UP000054241};
RN [1] {ECO:0000313|EMBL:KUM92551.1, ECO:0000313|Proteomes:UP000054241}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40189 {ECO:0000313|EMBL:KUM92551.1,
RC ECO:0000313|Proteomes:UP000054241};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces cellostaticus DSM 40189, type strain
RT for the species Streptomyces cellostaticus.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC {ECO:0000256|ARBA:ARBA00006479}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUM92551.1}.
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DR EMBL; LMWL01000062; KUM92551.1; -; Genomic_DNA.
DR RefSeq; WP_067005871.1; NZ_KQ948036.1.
DR AlphaFoldDB; A0A101NGJ3; -.
DR STRING; 67285.AQI88_31930; -.
DR OrthoDB; 37575at2; -.
DR Proteomes; UP000054241; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000600; ROK.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR18964:SF149; BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE; 1.
DR PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR Pfam; PF09339; HTH_IclR; 1.
DR Pfam; PF00480; ROK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000054241}.
FT DOMAIN 20..60
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|Pfam:PF09339"
SQ SEQUENCE 385 AA; 40531 MW; AE2FA5C22C7D4987 CRC64;
MGQLTGGDPS LLRRINSAVV LHALRAADCA TLTEITRVTG LSRPTVEGVV EGLIEAGLVV
EKAAEEGTAR RQGRPARRFR FRAEAGHLLG LEIGAHRVAA LLSDLDGRVL GAQAKEVDET
APADERLDRL RGAVAELLRR AGIARSSLRA VGVGTPGILE ADGTVRLGTA LPQWTGLRLG
ERLSRSFKCP VLVENDANAA AVAEHWKGAA TETDDVVFVL AGLSPGAGSL IGGRLHRGYG
GAAGEIGALH LLGRGATPEA LLSTTDEPLH PLDEQAVAEV FALAREGDLR ARAAVERFIQ
RLVHDVAALV LALDPELVVI GGWAAGLDGV LEPLRRELAR YCLRPPRVTL SLLGEAAVAT
GALRLALDHV EEQLFAVDAT VTARR
//
