ID   A0A101NLG7_9ACTN        Unreviewed;       526 AA.
AC   A0A101NLG7;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Hydrolase {ECO:0000313|EMBL:KUM95217.1};
GN   ORFNames=AQI88_17645 {ECO:0000313|EMBL:KUM95217.1};
OS   Streptomyces cellostaticus.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=67285 {ECO:0000313|EMBL:KUM95217.1, ECO:0000313|Proteomes:UP000054241};
RN   [1] {ECO:0000313|EMBL:KUM95217.1, ECO:0000313|Proteomes:UP000054241}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40189 {ECO:0000313|EMBL:KUM95217.1,
RC   ECO:0000313|Proteomes:UP000054241};
RA   Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT   "Draft genome sequence of Streptomyces cellostaticus DSM 40189, type strain
RT   for the species Streptomyces cellostaticus.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase S33 family.
CC       {ECO:0000256|ARBA:ARBA00010088}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUM95217.1}.
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DR   EMBL; LMWL01000031; KUM95217.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A101NLG7; -.
DR   STRING; 67285.AQI88_17645; -.
DR   ESTHER; 9actn-a0a101nlg7; Tiancimycin-TnmK-Tripeptidase-HIP.
DR   Proteomes; UP000054241; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   InterPro; IPR013595; Pept_S33_TAP-like_C.
DR   PANTHER; PTHR43248; 2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE; 1.
DR   PANTHER; PTHR43248:SF29; AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00561; Abhydrolase_1; 1.
DR   Pfam; PF08386; Abhydrolase_4; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:KUM95217.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054241};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           30..526
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5007101669"
FT   DOMAIN          91..276
FT                   /note="AB hydrolase-1"
FT                   /evidence="ECO:0000259|Pfam:PF00561"
FT   DOMAIN          402..499
FT                   /note="Peptidase S33 tripeptidyl aminopeptidase-like C-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08386"
FT   REGION          330..365
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   526 AA;  57855 MW;  AB49E709B1F658D5 CRC64;
     MRIGRMAPLL AVGITATLVP ALAPTQASAA EPLKRFENQK PSWHRCDRSM PAAFQCATIK
     VPVDYSRPTA KTLKLAVSRM KTSVPGKRHG AILFNPGGPG GEGLDMPVMM KDTMPKKVRE
     QYDLIGFDPR GVGRSSPVTC GLTTAEQNIE HAYRPKTFDR DVKWARTVAG KCRAKNGDTL
     AHITTRNTAR DMDVIRAVLG EKKISYLGYS YGTYLGAVYA QMFPERTDRF VLDSAVDPAR
     VWRGMLQVWA EGTEPAFTRW TKWTAQHHRT YQLGDTPAKV KKTFWDLIAR ADRDPIESGG
     EKLTGDDIRA ALRAEFFSPR NAAENVVELK KAADGTPASP RIAAPDDEQG PRRFAAPAAQ
     PPDDNSSAAF WTVVCGDTAA WPRDPDQYRR DAIRNKAKYP LYGDFGSNIT PCAFWSRTAE
     PVTTVDNNVG LLTVQNQWDS QTPLTSGLGM HHALKGSRMV YVKGGEGHGV YSDDPRWCAN
     RTVNAYLSTG KLPAQDVTCK APARQNEGVN QRIVPAPQQA PGAPRF
//