ID A0A101NP49_9ACTN Unreviewed; 319 AA.
AC A0A101NP49;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=Beta-lactamase class A catalytic domain-containing protein {ECO:0000259|Pfam:PF13354};
GN ORFNames=AQI88_12140 {ECO:0000313|EMBL:KUM96597.1};
OS Streptomyces cellostaticus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=67285 {ECO:0000313|EMBL:KUM96597.1, ECO:0000313|Proteomes:UP000054241};
RN [1] {ECO:0000313|EMBL:KUM96597.1, ECO:0000313|Proteomes:UP000054241}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40189 {ECO:0000313|EMBL:KUM96597.1,
RC ECO:0000313|Proteomes:UP000054241};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces cellostaticus DSM 40189, type strain
RT for the species Streptomyces cellostaticus.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUM96597.1}.
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DR EMBL; LMWL01000018; KUM96597.1; -; Genomic_DNA.
DR RefSeq; WP_066997162.1; NZ_KQ948019.1.
DR AlphaFoldDB; A0A101NP49; -.
DR STRING; 67285.AQI88_12140; -.
DR OrthoDB; 3524371at2; -.
DR Proteomes; UP000054241; Unassembled WGS sequence.
DR GO; GO:0008800; F:beta-lactamase activity; IEA:InterPro.
DR GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR045155; Beta-lactam_cat.
DR InterPro; IPR000871; Beta-lactam_class-A.
DR PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR PANTHER; PTHR35333:SF4; SLR0121 PROTEIN; 1.
DR Pfam; PF13354; Beta-lactamase2; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054241}.
FT DOMAIN 152..290
FT /note="Beta-lactamase class A catalytic"
FT /evidence="ECO:0000259|Pfam:PF13354"
FT REGION 50..78
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..65
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 319 AA; 32175 MW; 95D5AAA2CE78F7D2 CRC64;
MESSRAGRRR ARRARRRPLL STALAVVAVA GVTAGSTVCV KARAHSGAGA VSSAASPSAS
SSAAAGEEAS VERATSPSAV DRKASLAKAM ASVTVPSGAE VSAAVLELDS GQSAAYGEAA
FDTASIVKVD ILATLLLQAQ DAGRQPTAAE RAYAAKMIEN SDNASATALW HTIGRAEGLD
AANERFGLSA TSGGDGELWG LTQTTAADQL VLLQQVFGEE SLLSAASRTY VQGLMKAVEA
DQRWGVSAAA AGSSWALKNG WLPRSTTGLW DVNSIGRVTV DGADYLVAVL SKGTASQAKG
IALVEAAAKA AVAGFASAP
//
