ID A0A101NXV7_9ACTN Unreviewed; 533 AA.
AC A0A101NXV7;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=AQI95_30870 {ECO:0000313|EMBL:KUN01341.1};
OS Streptomyces yokosukanensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=67386 {ECO:0000313|EMBL:KUN01341.1, ECO:0000313|Proteomes:UP000053127};
RN [1] {ECO:0000313|EMBL:KUN01341.1, ECO:0000313|Proteomes:UP000053127}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40224 {ECO:0000313|EMBL:KUN01341.1,
RC ECO:0000313|Proteomes:UP000053127};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces yokosukanensis DSM 40224, type
RT strain for the species Streptomyces yokosukanensis.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUN01341.1}.
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DR EMBL; LMWN01000043; KUN01341.1; -; Genomic_DNA.
DR RefSeq; WP_067131253.1; NZ_KQ948219.1.
DR AlphaFoldDB; A0A101NXV7; -.
DR STRING; 67386.AQI95_30870; -.
DR OrthoDB; 9763537at2; -.
DR Proteomes; UP000053127; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06568; GH20_SpHex_like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000053127};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..37
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 38..533
FT /note="beta-N-acetylhexosaminidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007102075"
FT DOMAIN 45..172
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 176..495
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 339
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 533 AA; 57441 MW; B82A77A6FB3C24CC CRC64;
MRRNHSTTPR TPRILGSLLL LAAAGAFTLG AAPTAQAAAP TPLDRVVPAP ASVEPGGSPY
RITRATRVRV DAVAEVRRVG SYLAGILRPS TGFSLPLTDH GTGGIRLHLA KGDFGAEGYR
LHSDAGGVTI TAGAPAGLFH GVQTLRQLLP AAVEKKAVQS GPWQIAGGTV EDRPRYSYRG
AMLDVSRHFF TVAQVERYID QLALYKINEL HLHLSDDQGW RIAVDSWPRL AAYGGSTEVG
GGKGGYYTKA EYREIVSYAA SRYLEVVPEL DMPGHSNAAL ASYAQLNCNG QAPPLYTGTE
VGFSSLCVNK EVTYDFVNDV VRELAALTPG RYLHIGGDEA HSTSHTDYVT FMDRVQPIVA
KYGKTVVGWH QLTGAHPAKG ALAQYWGLDS TSAAEKAQVA GAAQNGTGLI LSPADRVYLD
MKYTKDTKLG LDWAGLVEVR RSYDWNPGAY LPGAPASAVR GVEAPLWSET LKTNADIDYM
AFPRLPGAAE LGWSPAATHD WDTYKVRLAA QAPRWEALGI DYYRSPQVPW PAK
//
