ID   A0A101NZI5_9ACTN        Unreviewed;       412 AA.
AC   A0A101NZI5;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   SubName: Full=3-oxoacyl-ACP synthase {ECO:0000313|EMBL:KUN02175.1};
DE            EC=2.3.1.179 {ECO:0000313|EMBL:KUN02175.1};
GN   ORFNames=AQI95_29035 {ECO:0000313|EMBL:KUN02175.1};
OS   Streptomyces yokosukanensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=67386 {ECO:0000313|EMBL:KUN02175.1, ECO:0000313|Proteomes:UP000053127};
RN   [1] {ECO:0000313|EMBL:KUN02175.1, ECO:0000313|Proteomes:UP000053127}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40224 {ECO:0000313|EMBL:KUN02175.1,
RC   ECO:0000313|Proteomes:UP000053127};
RA   Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT   "Draft genome sequence of Streptomyces yokosukanensis DSM 40224, type
RT   strain for the species Streptomyces yokosukanensis.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC       synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC       ECO:0000256|RuleBase:RU003694}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUN02175.1}.
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DR   EMBL; LMWN01000040; KUN02175.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A101NZI5; -.
DR   STRING; 67386.AQI95_29035; -.
DR   Proteomes; UP000053127; Unassembled WGS sequence.
DR   GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR   CDD; cd00834; KAS_I_II; 1.
DR   Gene3D; 3.40.47.10; -; 1.
DR   InterPro; IPR000794; Beta-ketoacyl_synthase.
DR   InterPro; IPR018201; Ketoacyl_synth_AS.
DR   InterPro; IPR014031; Ketoacyl_synth_C.
DR   InterPro; IPR014030; Ketoacyl_synth_N.
DR   InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR11712:SF336; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR   Pfam; PF00109; ketoacyl-synt; 1.
DR   Pfam; PF02801; Ketoacyl-synt_C; 1.
DR   SMART; SM00825; PKS_KS; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 2.
DR   PROSITE; PS00606; KS3_1; 1.
DR   PROSITE; PS52004; KS3_2; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW   ECO:0000313|EMBL:KUN02175.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053127};
KW   Transferase {ECO:0000256|RuleBase:RU003694, ECO:0000313|EMBL:KUN02175.1}.
FT   DOMAIN          1..403
FT                   /note="Ketosynthase family 3 (KS3)"
FT                   /evidence="ECO:0000259|PROSITE:PS52004"
SQ   SEQUENCE   412 AA;  42071 MW;  6DF9E4EB6CFEA750 CRC64;
     MTPLGSDVAG TWQGLLEGRC GVRQLHDEEF DGLPVRIAAP VAVEPAELLS RREMRTMSRC
     AQFALIAARE AWGDAGFGTE DIRNEVLAAG RVGVSMGTIV GGAPVLVAAE HTLSARGARF
     VSPHTAPMVV PNSAAAQVAL DLGARGEART VVSACASGTE AIGQAIDRIR DGHVDIVLAG
     GTEAVITPSV MASFTAMRAL SPGTEGPEAA SRPFDKARDG FVLGEGAGVV VLEAEEHARA
     RGARIYGEAA GWGLSADAHH MVAPRPDGAG IVDALHKALA DAGAQPHEVA HVNAHATATP
     AGDAAEALAL QEVFGAGATI PVTAPKGALG HLQGAAGGVE AVAAVLTLHH RLIPPTIGCD
     NPDEGADLDI VADAPRPLPE KGDLVLSNSY GFGGHNAVLA FRRYTDMHSE VG
//