ID A0A101QT58_9ACTN Unreviewed; 477 AA.
AC A0A101QT58;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Terpene synthase {ECO:0000256|RuleBase:RU366034};
DE EC=4.2.3.- {ECO:0000256|RuleBase:RU366034};
GN ORFNames=AQJ30_25350 {ECO:0000313|EMBL:KUN35462.1};
OS Streptomyces longwoodensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=68231 {ECO:0000313|EMBL:KUN35462.1, ECO:0000313|Proteomes:UP000053271};
RN [1] {ECO:0000313|EMBL:KUN35462.1, ECO:0000313|Proteomes:UP000053271}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 41677 {ECO:0000313|EMBL:KUN35462.1,
RC ECO:0000313|Proteomes:UP000053271};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces longwoodensis DSM 41677, type strain
RT for the species Streptomyces longwoodensis.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(E)-2-methylgeranyl diphosphate + H2O = 2-methylisoborneol +
CC diphosphate; Xref=Rhea:RHEA:32571, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:61984, ChEBI:CHEBI:61987;
CC EC=4.2.3.118; Evidence={ECO:0000256|ARBA:ARBA00035573};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946,
CC ECO:0000256|RuleBase:RU366034};
CC -!- SIMILARITY: Belongs to the terpene synthase family. 2-methylisoborneol
CC synthase subfamily. {ECO:0000256|ARBA:ARBA00035653}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUN35462.1}.
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DR EMBL; LMWS01000032; KUN35462.1; -; Genomic_DNA.
DR RefSeq; WP_067238381.1; NZ_KQ948558.1.
DR AlphaFoldDB; A0A101QT58; -.
DR STRING; 68231.AQJ30_25350; -.
DR Proteomes; UP000053271; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010333; F:terpene synthase activity; IEA:InterPro.
DR GO; GO:0042214; P:terpene metabolic process; IEA:InterPro.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR047945; MIB_synthase.
DR InterPro; IPR034686; Terpene_cyclase-like_2.
DR NCBIfam; NF041167; f2_encap_cargo2; 1.
DR PANTHER; PTHR35201; TERPENE SYNTHASE; 1.
DR PANTHER; PTHR35201:SF4; TERPENE SYNTHASE; 1.
DR Pfam; PF19086; Terpene_syn_C_2; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01020; Terpene_Cyclase_Like_2; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|RuleBase:RU366034};
KW Magnesium {ECO:0000256|RuleBase:RU366034};
KW Metal-binding {ECO:0000256|RuleBase:RU366034};
KW Reference proteome {ECO:0000313|Proteomes:UP000053271}.
FT REGION 1..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 133..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..27
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..86
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 477 AA; 51235 MW; A8AEDE7C4C4E6CA4 CRC64;
MPDSGSLGPP TSLPEQPPAP PATTPDAPAA TAPDRPVTSS AAHFLAGLHP PVTTPSSSPS
PPSPSTPPAA WTPPSPPSPP SPSLPPASDV LVRNAPDLAA VPGTSDVSAS DSVVRRLLGG
PTGLGTTALS LARKQAAVPP DGAPAPSGPS AEGPVVPGLY HHPILEPDPV RVAEVSRRIK
QWAEDEVQLY PQEWEGQFDG FSVGRYMVAC HPDAPTVDHL MLATRLMVAE NAVDDCYCED
HGGSPVGLGG RLLLAHTALD HLHTTAEYAP QWQESLGSDA PRRAYRSAMD HFVRAATPSQ
ADRFRHDMAR LHLGYLAEAA WAETGHVPEV WEYLAMRQFN NFRPCPTITD TVGGYELPAD
LHARPDMQRV IALAGNATTI VNDLYSYTKE LNSPGRHLNL PVVIAEREHL SDRDAYLKAV
EVHNELMHAF EAAAAQLAAD CPVPAVLRFL RGVAAWVDGN HDWHRTNTYR YSLPDFW
//
