ID   A0A101QUU6_9ACTN        Unreviewed;       288 AA.
AC   A0A101QUU6;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Tyrosinase {ECO:0000313|EMBL:KUN36440.1};
GN   ORFNames=AQJ30_21315 {ECO:0000313|EMBL:KUN36440.1};
OS   Streptomyces longwoodensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=68231 {ECO:0000313|EMBL:KUN36440.1, ECO:0000313|Proteomes:UP000053271};
RN   [1] {ECO:0000313|EMBL:KUN36440.1, ECO:0000313|Proteomes:UP000053271}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 41677 {ECO:0000313|EMBL:KUN36440.1,
RC   ECO:0000313|Proteomes:UP000053271};
RA   Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT   "Draft genome sequence of Streptomyces longwoodensis DSM 41677, type strain
RT   for the species Streptomyces longwoodensis.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Cu(2+); Xref=ChEBI:CHEBI:29036;
CC         Evidence={ECO:0000256|ARBA:ARBA00001973};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUN36440.1}.
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DR   EMBL; LMWS01000024; KUN36440.1; -; Genomic_DNA.
DR   RefSeq; WP_067236421.1; NZ_KQ948555.1.
DR   AlphaFoldDB; A0A101QUU6; -.
DR   STRING; 68231.AQJ30_21315; -.
DR   Proteomes; UP000053271; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR   InterPro; IPR008922; Di-copper_centre_dom_sf.
DR   InterPro; IPR002227; Tyrosinase_Cu-bd.
DR   PANTHER; PTHR11474:SF124; TYROSINASE; 1.
DR   PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR   Pfam; PF00264; Tyrosinase; 1.
DR   PRINTS; PR00092; TYROSINASE.
DR   SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR   PROSITE; PS00497; TYROSINASE_1; 1.
DR   PROSITE; PS00498; TYROSINASE_2; 1.
PE   4: Predicted;
KW   Copper {ECO:0000256|ARBA:ARBA00023008};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053271}.
FT   DOMAIN          55..72
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00497"
FT   DOMAIN          219..230
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00498"
SQ   SEQUENCE   288 AA;  33069 MW;  8A8AFBCD3EE657D6 CRC64;
     MVYTRKDVSR LTASEKRRFV NALLALKRRG EYDEFVRMHI DHYVSDGEGG LRAAHMAPSF
     LPWHRRFLLD LERALRRVDS SVTVPYWDWT RQRSATSVPW TKDLLGGNGR RSDHRVTTGP
     FAHATGNWPI KENVTDGVFL TRDLGRASNP IELPTAAELE GALRDPVYDT SPWDSTSTRG
     FRNKLEGWGS GRGSAAWRNH NRVHRWVGGN MVGGASVNDP VFWLHHAFVD LQWTRWQQRH
     RDARYLPAQP PRFGDPQRDR VVARHEDLPP WGVTPAQLED VSGIYRYA
//