ID A0A101QWY1_9ACTN Unreviewed; 332 AA.
AC A0A101QWY1;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=ATP-dependent DNA ligase {ECO:0000313|EMBL:KUN37675.1};
GN ORFNames=AQJ30_15435 {ECO:0000313|EMBL:KUN37675.1};
OS Streptomyces longwoodensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=68231 {ECO:0000313|EMBL:KUN37675.1, ECO:0000313|Proteomes:UP000053271};
RN [1] {ECO:0000313|EMBL:KUN37675.1, ECO:0000313|Proteomes:UP000053271}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 41677 {ECO:0000313|EMBL:KUN37675.1,
RC ECO:0000313|Proteomes:UP000053271};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces longwoodensis DSM 41677, type strain
RT for the species Streptomyces longwoodensis.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUN37675.1}.
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DR EMBL; LMWS01000018; KUN37675.1; -; Genomic_DNA.
DR RefSeq; WP_067233752.1; NZ_KQ948553.1.
DR AlphaFoldDB; A0A101QWY1; -.
DR STRING; 68231.AQJ30_15435; -.
DR Proteomes; UP000053271; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd07905; Adenylation_DNA_ligase_LigC; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR044119; Adenylation_LigC-like.
DR InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR PANTHER; PTHR45674:SF9; DNA LIGASE 3; 1.
DR Pfam; PF01068; DNA_ligase_A_M; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:KUN37675.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053271}.
FT DOMAIN 114..230
FT /note="ATP-dependent DNA ligase family profile"
FT /evidence="ECO:0000259|PROSITE:PS50160"
FT REGION 309..332
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 332 AA; 36211 MW; 4F8823EF7BA61CA2 CRC64;
MTWSLPQPML TTAVDSPALP AGWAAEPKWD GYRAQLAVHT GGRVLLRSRQ GTDMTTAFPE
IRAASLAQLP ADTGLDGELV VWEQGRLAFE RLQQRLARRG SGSAHGARQW PAHYVVFDLV
HADGTDLTSW PYERRRAALE ALVAERQLEP PLTLCPSTTD PAVAQGWLEW TAAGLEGLCF
KRLSDPYTGG ARAWRKYKVR ITTEAIIGAV TGTLGAPRAA LLGRYDTAGR LRYTGRSTTL
SAHLARALGD VLVRPAHVHP WEGWTFSAGW GTRRMLDVVL VEPAVVLEVA VDVARDAAGR
FRHPARPHRI RTDIDTAQVP RFGEPGADSA GP
//
