ID A0A101S165_9ACTN Unreviewed; 784 AA.
AC A0A101S165;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Glycosyl hydrolase {ECO:0000313|EMBL:KUN65406.1};
GN ORFNames=AQJ54_21540 {ECO:0000313|EMBL:KUN65406.1};
OS Streptomyces griseorubiginosus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=67304 {ECO:0000313|EMBL:KUN65406.1, ECO:0000313|Proteomes:UP000054375};
RN [1] {ECO:0000313|EMBL:KUN65406.1, ECO:0000313|Proteomes:UP000054375}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40469 {ECO:0000313|EMBL:KUN65406.1,
RC ECO:0000313|Proteomes:UP000054375};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces griseorubiginosus DSM 40469, type
RT strain for the species Streptomyces griseorubiginosus.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 65 family.
CC {ECO:0000256|ARBA:ARBA00006768}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUN65406.1}.
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DR EMBL; LMWV01000017; KUN65406.1; -; Genomic_DNA.
DR RefSeq; WP_062239803.1; NZ_KQ948737.1.
DR AlphaFoldDB; A0A101S165; -.
DR Proteomes; UP000054375; Unassembled WGS sequence.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 2.70.98.40; Glycoside hydrolase, family 65, N-terminal domain; 1.
DR Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR005194; Glyco_hydro_65_C.
DR InterPro; IPR005195; Glyco_hydro_65_M.
DR InterPro; IPR005196; Glyco_hydro_65_N.
DR InterPro; IPR037018; Glyco_hydro_65_N_sf.
DR InterPro; IPR017045; Malt_Pase/Glycosyl_Hdrlase.
DR PANTHER; PTHR11051; GLYCOSYL HYDROLASE-RELATED; 1.
DR PANTHER; PTHR11051:SF13; GLYCOSYL TRANSFERASE-RELATED; 1.
DR Pfam; PF03633; Glyco_hydro_65C; 1.
DR Pfam; PF03632; Glyco_hydro_65m; 1.
DR Pfam; PF03636; Glyco_hydro_65N; 1.
DR PIRSF; PIRSF036289; Glycosyl_hydrolase_malt_phosph; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000313|EMBL:KUN65406.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054375}.
FT DOMAIN 16..270
FT /note="Glycoside hydrolase family 65 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03636"
FT DOMAIN 327..684
FT /note="Glycoside hydrolase family 65 central catalytic"
FT /evidence="ECO:0000259|Pfam:PF03632"
FT DOMAIN 693..754
FT /note="Glycoside hydrolase family 65 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03633"
FT REGION 748..784
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 488
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR036289-50"
FT BINDING 361..362
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR036289-51"
FT BINDING 592..593
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR036289-51"
SQ SEQUENCE 784 AA; 86369 MW; 9A05FEB412D46842 CRC64;
MITQRSYTVE PWAVRETALN LDVLAQSESV FALSNGHVGW RGNLDEGEPH GLPGSYLNGV
HELHPLPYAE AGYGYPESGQ TVIDVTNGKI LRLLVDDEPF DLRYGRLVSH ERTLDLRRGV
LERTCEWISP AGSRIRVRST RLVSLTQRAI AAVAYEVEPV DSRTRVVIQS ELVTNESLPS
PNGDPRAAKA LKSPLEHEEG FADGTRLRLV HRTRQSGLRV AVAADHVIDG PGRTTTSSEE
MVDLARLTVT SVLEPGQRLR VEKLVAHGWS GVRSRPAMSD QVDAALAAAA HSGWDGLLDE
QRGYLDDFWA RADVEVDGDE EIQQAVRFAL FHVLQAGARA EQRAIPAKGL TGSGYDGHAF
WDTETFVLPL LTYTEPRAVA EALRWRQHTL PAARDRAVQL GLRGAAFPWR TIDGSEGSAY
WPAGTAAFHV NAAVADAVVR YTEATGDLDF ERDTGVELLV ETARLWRSLG HHDHRGVFHI
DGVTGPDEYS AVADDNTYTN LMARANLLAA AEACARHPHQ AAALGVDDEE SAAWRDAAEA
VHIPYNDELG VHEQHAGFTR HQQWDFAGTR ADQYPLMLHF PYFDLYRKQV VKQADLVLAM
YLCSNWFEEF HDEERIARNF AYYEPLTVRD SSLSACVQAV VAARAGHLSL AYAYTAEAAL
MDLADLENNT RDGLHIASLA GTWTALVAGF GGLRRDGASL RFAPRLPERF SRLAFNLRLL
DRCLRVEIGP DKATYTLVSG APLTISHHGT PLTLNGDGPV VRPVPAPRDR PAPDQPPHRA
PHAR
//
