ID   A0A101S1T0_9ACTN        Unreviewed;       740 AA.
AC   A0A101S1T0;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Alpha-L-fucosidase {ECO:0000313|EMBL:KUN65884.1};
GN   ORFNames=AQJ54_19465 {ECO:0000313|EMBL:KUN65884.1};
OS   Streptomyces griseorubiginosus.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=67304 {ECO:0000313|EMBL:KUN65884.1, ECO:0000313|Proteomes:UP000054375};
RN   [1] {ECO:0000313|EMBL:KUN65884.1, ECO:0000313|Proteomes:UP000054375}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40469 {ECO:0000313|EMBL:KUN65884.1,
RC   ECO:0000313|Proteomes:UP000054375};
RA   Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT   "Draft genome sequence of Streptomyces griseorubiginosus DSM 40469, type
RT   strain for the species Streptomyces griseorubiginosus.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-
CC       1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the
CC       carbohydrate moieties of glycoproteins.
CC       {ECO:0000256|ARBA:ARBA00004071}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUN65884.1}.
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DR   EMBL; LMWV01000016; KUN65884.1; -; Genomic_DNA.
DR   RefSeq; WP_062238976.1; NZ_KQ948737.1.
DR   AlphaFoldDB; A0A101S1T0; -.
DR   Proteomes; UP000054375; Unassembled WGS sequence.
DR   GO; GO:0004560; F:alpha-L-fucosidase activity; IEA:InterPro.
DR   GO; GO:0006004; P:fucose metabolic process; IEA:InterPro.
DR   CDD; cd00161; RICIN; 1.
DR   Gene3D; 2.80.10.50; -; 1.
DR   Gene3D; 2.60.20.10; Crystallins; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR016286; FUC_metazoa-typ.
DR   InterPro; IPR011024; G_crystallin-like.
DR   InterPro; IPR000933; Glyco_hydro_29.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR035992; Ricin_B-like_lectins.
DR   InterPro; IPR000772; Ricin_B_lectin.
DR   InterPro; IPR006311; TAT_signal.
DR   PANTHER; PTHR10030; ALPHA-L-FUCOSIDASE; 1.
DR   PANTHER; PTHR10030:SF46; ALPHA-L-FUCOSIDASE-RELATED; 1.
DR   Pfam; PF01120; Alpha_L_fucos; 1.
DR   Pfam; PF14200; RicinB_lectin_2; 2.
DR   PRINTS; PR00741; GLHYDRLASE29.
DR   SMART; SM00812; Alpha_L_fucos; 1.
DR   SMART; SM00458; RICIN; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF49695; gamma-Crystallin-like; 1.
DR   SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR   PROSITE; PS50231; RICIN_B_LECTIN; 1.
DR   PROSITE; PS51318; TAT; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054375};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..31
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           32..740
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5007105618"
FT   DOMAIN          604..738
FT                   /note="Ricin B lectin"
FT                   /evidence="ECO:0000259|SMART:SM00458"
SQ   SEQUENCE   740 AA;  80072 MW;  3FF1247E7F1DD879 CRC64;
     MISRRQFLAS ATGVAAAAAV GNVLTAGTAR AATTYTPTWA SVDQHTASPE WFKDAKFGIY
     YHWGVFSVPA YDSEWYPRNM YISGSKANTH HIATYGDPSA WPYHNFINGA NDLNGNFNKF
     APKLKSAGGN FDPDEWAQLF ADAGARFAGP VAEHHDGFSM WNSSVNEWNS VAKGPQLNLL
     QLFTDSIRAK GLKLLVAMHH AFNFNGFYDH APAQSDPSLQ KLYGQLGTTA ENQLWYDKLK
     EVIDLAKPDI IWQDFDLNKV NQTQQLNFLS YYYNQAEAWG REVVATYKDG FNGHGEVFDY
     ERGGPGDITA PYWLTDDSIS SSSWCYTNGI GYYSTQQMLH SLIDRVSKNG NMLLNIAPMA
     DGTIPQAQKD ILLGIGDYLK RFGESVYSTR AWTTYGEGPT HMGGGAFTAP KVGTAQDIRF
     TRSKNNTVLY ATVLGWPGSA LNISTLNSAR INVGSLTSAQ LLNPTAGTYT SLPTPTQDSA
     GLHVTLPSSS APFSALAYVV KLTFSGQIPT LKPQSGAVAY QDVNYLGGSA VLQIGTYTAD
     QLSLAGLPSR TLSSLKLAPG HQIIGYSGDN FTGTAWTFTA DTADLRPSGT NDAVVSMKVQ
     LNPSAWFRIT NVTDGLVLDS GGNVPSGSNL KQWTWNGSTN LQWQAVELGT GYYKLVNRAN
     GMVADGGGAT TNGSPALEAT WDGSTKQQWQ LRYQGGGRYW ITNRATGLVL DGGGNVPSGS
     VTKQWSGNSS TNVQWTFTAV
//