ID A0A101SCB7_9ACTN Unreviewed; 313 AA.
AC A0A101SCB7; A0A117PDK4;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=N,N'-diacetyllegionaminic acid synthase {ECO:0000313|EMBL:AYC38994.1};
DE EC=2.5.1.101 {ECO:0000313|EMBL:AYC38994.1};
DE SubName: Full=N-acetylneuraminate synthase {ECO:0000313|EMBL:KUN71622.1};
GN Name=legI {ECO:0000313|EMBL:AYC38994.1};
GN ORFNames=AQJ54_02365 {ECO:0000313|EMBL:KUN71622.1}, DWG14_03226
GN {ECO:0000313|EMBL:AYC38994.1};
OS Streptomyces griseorubiginosus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=67304 {ECO:0000313|EMBL:KUN71622.1, ECO:0000313|Proteomes:UP000054375};
RN [1] {ECO:0000313|EMBL:KUN71622.1, ECO:0000313|Proteomes:UP000054375}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40469 {ECO:0000313|EMBL:KUN71622.1,
RC ECO:0000313|Proteomes:UP000054375};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces griseorubiginosus DSM 40469, type
RT strain for the species Streptomyces griseorubiginosus.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AYC38994.1, ECO:0000313|Proteomes:UP000265765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3E-1 {ECO:0000313|EMBL:AYC38994.1,
RC ECO:0000313|Proteomes:UP000265765};
RA Kang H.J., Kim S.B.;
RT "Production of Trimethoprim by Streptomyces sp. 3E-1.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP032427; AYC38994.1; -; Genomic_DNA.
DR EMBL; LMWV01000002; KUN71622.1; -; Genomic_DNA.
DR RefSeq; WP_062023691.1; NZ_KQ948734.1.
DR AlphaFoldDB; A0A101SCB7; -.
DR KEGG; sge:DWG14_03226; -.
DR OrthoDB; 9814210at2; -.
DR Proteomes; UP000054375; Unassembled WGS sequence.
DR Proteomes; UP000265765; Chromosome.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR013132; Neu5Ac_N.
DR PANTHER; PTHR42966:SF3; BLR5971 PROTEIN; 1.
DR PANTHER; PTHR42966; N-ACETYLNEURAMINATE SYNTHASE; 1.
DR Pfam; PF03102; NeuB; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054375};
KW Transferase {ECO:0000313|EMBL:AYC38994.1}.
FT DOMAIN 42..278
FT /note="N-acetylneuraminic acid synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03102"
SQ SEQUENCE 313 AA; 34560 MW; B3C68CF329FD5BEA CRC64;
MSVNSRLRTF GTERIAGPGQ PVYICGEIGI NHNGELENAF KLIDVAAEAG CDAVKFQKRT
PEICTPRDQW DIERDTPWGR MTYIDYRHRV EFGEDEYRQI DEYCKEKGIA WFASPWDTEA
VAFLEKFDVP AHKVASASLT DDELLRALRA TGRTIILSSG MSTPKQIRHA VEVLGSDNIL
LCHATSTYPA KAEELNLRVI NTLQEEYPNV PIGYSGHETG LQTTLAAVAL GATFVERHIT
LDRAMWGSDQ AASVEPQGLQ RLVRDIRTIE ASLGDGVKKV YDSELGPMKK LRRVTGVVAE
AEIAAAAGEP VSV
//
