ID A0A101TFL5_9ACTN Unreviewed; 490 AA.
AC A0A101TFL5;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE SubName: Full=C4-dicarboxylate transporter {ECO:0000313|EMBL:KUN91418.1};
GN ORFNames=AQJ67_42385 {ECO:0000313|EMBL:KUN91418.1};
OS Streptomyces caeruleatus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=661399 {ECO:0000313|EMBL:KUN91418.1, ECO:0000313|Proteomes:UP000053429};
RN [1] {ECO:0000313|EMBL:KUN91418.1, ECO:0000313|Proteomes:UP000053429}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL B-24802 {ECO:0000313|EMBL:KUN91418.1,
RC ECO:0000313|Proteomes:UP000053429};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces caeruleatus NRRL B-24802, type
RT strain for the species Streptomyces caeruleatus.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUN91418.1}.
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DR EMBL; LMWY01000065; KUN91418.1; -; Genomic_DNA.
DR RefSeq; WP_062725164.1; NZ_KQ948948.1.
DR AlphaFoldDB; A0A101TFL5; -.
DR STRING; 661399.AQJ67_42385; -.
DR OrthoDB; 9766690at2; -.
DR Proteomes; UP000053429; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR GO; GO:0046942; P:carboxylic acid transport; IEA:UniProt.
DR Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR InterPro; IPR001991; Na-dicarboxylate_symporter.
DR InterPro; IPR018107; Na-dicarboxylate_symporter_CS.
DR InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR PANTHER; PTHR42865:SF1; AEROBIC C4-DICARBOXYLATE TRANSPORT PROTEIN; 1.
DR PANTHER; PTHR42865; PROTON/GLUTAMATE-ASPARTATE SYMPORTER; 1.
DR Pfam; PF00375; SDF; 1.
DR PRINTS; PR00173; EDTRNSPORT.
DR SUPFAM; SSF118215; Proton glutamate symport protein; 1.
DR PROSITE; PS00714; NA_DICARBOXYL_SYMP_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053429};
KW Symport {ECO:0000256|ARBA:ARBA00022847};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 198..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 319..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 362..385
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 433..490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 444..462
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 490 AA; 51020 MW; 26D63175AA95D9BB CRC64;
MPPSESSLPR RVARTLRTSL FAQVACALVL GIVVGKLWPG FAADLQPLGD GFIRLIKTII
SPLVFCVVVV GIAKAGDLKA FGRIGLKALI WFEVASTLAL VIGLLAANVV QPGSGMNVDP
STLNASAVDA KTGGGHLPST AQFVLEAIPT SFIGAFAENS LLQVLILACL VGAALLHLGH
TKVPKVLPAI EQAQEIIFAI VGFVMRLAPI AVFGAMAVLI GNYGLGVIET YGKLIILCYA
AAALFIALLA VALKVVTGLS LWKFLRYIRE EMLLALGTAS TESVLPRVMQ KLRKAGARDD
AVGLVLPTGY SFNLDGASLY LSIGTLFIAQ AVGVDLSLSQ QITVVLVLML TSKGMAGIPG
SAFLALSATA SSLGAIPAGA VALLLGVDRI MDSMRVVTNL LGNCVAVFAV SRWEGALDRE
RARKVLDGEI VVQLDDEEPD GEGPEGAEPK KPELKKPDAA EPEKGVPVPS EDPVVAVPVR
TDKGASPEAG
//
