ID   A0A101U6J7_9ACTN        Unreviewed;       319 AA.
AC   A0A101U6J7;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   SubName: Full=Threonine dehydratase {ECO:0000313|EMBL:KUO04988.1};
GN   ORFNames=AQJ67_06180 {ECO:0000313|EMBL:KUO04988.1};
OS   Streptomyces caeruleatus.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=661399 {ECO:0000313|EMBL:KUO04988.1, ECO:0000313|Proteomes:UP000053429};
RN   [1] {ECO:0000313|EMBL:KUO04988.1, ECO:0000313|Proteomes:UP000053429}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL B-24802 {ECO:0000313|EMBL:KUO04988.1,
RC   ECO:0000313|Proteomes:UP000053429};
RA   Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT   "Draft genome sequence of Streptomyces caeruleatus NRRL B-24802, type
RT   strain for the species Streptomyces caeruleatus.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUO04988.1}.
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DR   EMBL; LMWY01000005; KUO04988.1; -; Genomic_DNA.
DR   RefSeq; WP_062717022.1; NZ_KQ948925.1.
DR   AlphaFoldDB; A0A101U6J7; -.
DR   STRING; 661399.AQJ67_06180; -.
DR   OrthoDB; 9811476at2; -.
DR   Proteomes; UP000053429; Unassembled WGS sequence.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:1901605; P:alpha-amino acid metabolic process; IEA:UniProt.
DR   CDD; cd01562; Thr-dehyd; 1.
DR   Gene3D; 3.40.50.1100; -; 2.
DR   InterPro; IPR000634; Ser/Thr_deHydtase_PyrdxlP-BS.
DR   InterPro; IPR001926; TrpB-like_PALP.
DR   InterPro; IPR036052; TrpB-like_PALP_sf.
DR   PANTHER; PTHR48078:SF6; ACT DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR48078; THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED; 1.
DR   Pfam; PF00291; PALP; 1.
DR   SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
DR   PROSITE; PS00165; DEHYDRATASE_SER_THR; 1.
PE   4: Predicted;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053429}.
FT   DOMAIN          16..301
FT                   /note="Tryptophan synthase beta chain-like PALP"
FT                   /evidence="ECO:0000259|Pfam:PF00291"
SQ   SEQUENCE   319 AA;  32260 MW;  4F5AC8C62474EA3D CRC64;
     MIGISDVEAA ADLIAAHVVH TPTVPSPALS ALLGVPVTAK LELLQRTGSF KARGATAKLL
     SLSDAQRAAG VVAVSGGNHG IALAMTAAVL DVKATVVMPR SAPARAVEIA RDAGASVRLT
     DDMDGAFSLV TRLRDEGLTL VHPFDDPLVI AGQGTVGLEL ADDAGELTDV IVSVGGGGLV
     AGVAVALRAR RPDVRIWGVE TEGAQAMSEA LAAGGPVPVT LSSIVSTLSA PAVSQLTYDH
     VSALVDEVLV VPDREAVRGV LELAEHAKVW TEPAAGCLLP AARQVLARAG DGARVGLVVC
     GGNATTGDVL RWAAAFGLR
//