ID A0A101UCF5_9ACTN Unreviewed; 588 AA.
AC A0A101UCF5;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Peptidase S8 {ECO:0000313|EMBL:KUO08024.1};
GN ORFNames=AQJ58_32190 {ECO:0000313|EMBL:KUO08024.1};
OS Streptomyces sp. DSM 15324.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1739111 {ECO:0000313|EMBL:KUO08024.1, ECO:0000313|Proteomes:UP000053431};
RN [1] {ECO:0000313|EMBL:KUO08024.1, ECO:0000313|Proteomes:UP000053431}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15324 {ECO:0000313|EMBL:KUO08024.1,
RC ECO:0000313|Proteomes:UP000053431};
RA Ruckert C., Winkler A., Kalinowski J., Wink J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces sp. DSM 15324, isolated from soil.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240,
CC ECO:0000256|RuleBase:RU003355}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUO08024.1}.
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DR EMBL; LMXA01000034; KUO08024.1; -; Genomic_DNA.
DR RefSeq; WP_067256548.1; NZ_KQ949034.1.
DR AlphaFoldDB; A0A101UCF5; -.
DR OrthoDB; 9813435at2; -.
DR Proteomes; UP000053431; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR002884; P_dom.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023827; Peptidase_S8_Asp-AS.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR PANTHER; PTHR43806:SF59; CEREVISIN-RELATED; 1.
DR PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR Pfam; PF01483; P_proprotein; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51829; P_HOMO_B; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00136; SUBTILASE_ASP; 1.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000053431};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..588
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007107861"
FT DOMAIN 471..588
FT /note="P/Homo B"
FT /evidence="ECO:0000259|PROSITE:PS51829"
FT ACT_SITE 172
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 212
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 404
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 588 AA; 59426 MW; 1031BAA1A8CD1A47 CRC64;
MLAATLGAAL ALGAPGALAG TLPVGPSTAP APAAKAHTPA AVPASQSATW VAGTRAYLVI
TAPGDSSAVR SAITANGGTV FSNFDAIGVI VAHSASSGFA ATMRDVPGVQ QVGATRTSDV
PADAYNPALP ANPAQASTPA GEPVRADMSQ IKADQAWAVN PGSASVTVGI LDTGVDDQHQ
DLAPNFDAAD SVSCAYGKPD TRAGAWRDVD THGTHVAGTI AAAKNGKGVV GVAPGVKIAA
VRVAEPGNAF FFAENTICGF VWAGDHGFKV TNNSYYTDPW QFNCPDNIDQ AAIIEGVKRA
QEYAEGKGSL QIAAAGNENY DLAHKTTDSA SPNDSTPVTR TITNACLDIP TELPGVVTVA
ANGTGVTKAS FSNYGQGVID VAAPGSNVYS TVPGGGYGSK SGTSMATPHV VGVAALIASA
NPGITPAQIR AKLAEQANDI ACPSDSRCTG TTANNSFFGE GQVDALKAVG TTPPAGTYFE
NLTDFAINDN ATVESPIVVT GVTGNAPATL KVGVDIKHTY IGDLKVDLVA PDGTVYTLHN
RAGGSADNIA QTYTVNASSE VANGTWKLRV NDNAASDTGK IDAWNLTF
//
