ID A0A101UPA6_9ACTN Unreviewed; 388 AA.
AC A0A101UPA6;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Saccharopine dehydrogenase {ECO:0000313|EMBL:KUO14398.1};
GN ORFNames=AQJ91_47110 {ECO:0000313|EMBL:KUO14398.1};
OS Streptomyces dysideae.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=909626 {ECO:0000313|EMBL:KUO14398.1, ECO:0000313|Proteomes:UP000053260};
RN [1] {ECO:0000313|EMBL:KUO14398.1, ECO:0000313|Proteomes:UP000053260}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RV15 {ECO:0000313|EMBL:KUO14398.1,
RC ECO:0000313|Proteomes:UP000053260};
RA Ruckert C., Abdelmohsen U.R., Winkler A., Hentschel U., Kalinowski J.,
RA Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces sp. RV15, isolated from a marine
RT sponge.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUO14398.1}.
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DR EMBL; LMXB01000153; KUO14398.1; -; Genomic_DNA.
DR RefSeq; WP_067036179.1; NZ_KQ949143.1.
DR AlphaFoldDB; A0A101UPA6; -.
DR STRING; 909626.AQJ91_47110; -.
DR OrthoDB; 973788at2; -.
DR Proteomes; UP000053260; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032095; Sacchrp_dh-like_C.
DR InterPro; IPR005097; Sacchrp_dh_NADP.
DR PANTHER; PTHR11133:SF25; ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11133; SACCHAROPINE DEHYDROGENASE; 1.
DR Pfam; PF16653; Sacchrp_dh_C; 1.
DR Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000053260}.
FT DOMAIN 15..129
FT /note="Saccharopine dehydrogenase NADP binding"
FT /evidence="ECO:0000259|Pfam:PF03435"
FT DOMAIN 133..376
FT /note="Saccharopine dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16653"
SQ SEQUENCE 388 AA; 41512 MW; 5FD8EE09D7F42DFA CRC64;
MSDRSSERVP ANGTVHWVGA GLSTGSGLAR LCDTADRVRL WHRTEERAAE ALAHLGLTGR
AEPSAYTLEA LAAALAPGDI VVSMLPAPEH AGILAACVRA RAHFACSSYV SDAVLELVPA
ATQAGIVVLT EAGLDPGIDH LFAHSLVARA REAIGDGTAA SYSLTSYCGG VPAVPNDFRY
RFSWAPAGVL NALRSPARYV EDGAETVAER PWEATRRHVV DGEAFEVYPN RDSVPFVEQY
GMPPAWKPQT FVRGTLRLEG WLRAWDAVFE ELKGGDDTRI AALARELAAT YPTTDADRDR
VVLAVSLSVR GGDGQAWAGS YLLDLVGDEE ESAMARCVSR PLALGVRHTL EGALPAGLNR
AAETAARSEE WLRELALDGV EFTLRVDA
//
