ID   A0A101UXU1_9ACTN        Unreviewed;       285 AA.
AC   A0A101UXU1;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Histidine-specific methyltransferase SAM-dependent domain-containing protein {ECO:0000259|Pfam:PF10017};
GN   ORFNames=AQJ91_23395 {ECO:0000313|EMBL:KUO18811.1};
OS   Streptomyces dysideae.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=909626 {ECO:0000313|EMBL:KUO18811.1, ECO:0000313|Proteomes:UP000053260};
RN   [1] {ECO:0000313|EMBL:KUO18811.1, ECO:0000313|Proteomes:UP000053260}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RV15 {ECO:0000313|EMBL:KUO18811.1,
RC   ECO:0000313|Proteomes:UP000053260};
RA   Ruckert C., Abdelmohsen U.R., Winkler A., Hentschel U., Kalinowski J.,
RA   Kampfer P., Glaeser S.;
RT   "Draft genome sequence of Streptomyces sp. RV15, isolated from a marine
RT   sponge.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUO18811.1}.
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DR   EMBL; LMXB01000058; KUO18811.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A101UXU1; -.
DR   STRING; 909626.AQJ91_23395; -.
DR   Proteomes; UP000053260; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR019257; MeTrfase_dom.
DR   InterPro; IPR017804; MeTrfase_EgtD-like.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF10017; Methyltransf_33; 1.
DR   PIRSF; PIRSF018005; UCP018005; 2.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000053260}.
FT   DOMAIN          27..156
FT                   /note="Histidine-specific methyltransferase SAM-dependent"
FT                   /evidence="ECO:0000259|Pfam:PF10017"
SQ   SEQUENCE   285 AA;  32592 MW;  C8B5ABEDDC3FED08 CRC64;
     MIEEDAPNLE NSTIELLGMS QGYLDGLLRR FKKVNIIDVG VGNAWPVKEL LGNLLEQGKL
     GRYIAVDISP EMLRIARDNI KEWFGGRVDF EDYEIDINRE GFGNLLAEDY IKKDSAETAN
     LVLLLGGTLG NMRSPDSALR VIHESMSFND FMVYTMKLDS EGTRRYFDFK VDPGDEVLPP
     IHGAVIDLLN IDPSLYQVEM GYDQLKHQRY ERIRLKKSIN IRFDFDDGEW PVALDKGESI
     LVWRGLQLSA QDVTDQLNRN DFYVLHASQT PNREYLLAVA EVNRD
//