ID A0A101UZV6_9ACTN Unreviewed; 607 AA.
AC A0A101UZV6;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=NADH dehydrogenase {ECO:0000313|EMBL:KUO19888.1};
GN ORFNames=AQJ91_17195 {ECO:0000313|EMBL:KUO19888.1};
OS Streptomyces dysideae.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=909626 {ECO:0000313|EMBL:KUO19888.1, ECO:0000313|Proteomes:UP000053260};
RN [1] {ECO:0000313|EMBL:KUO19888.1, ECO:0000313|Proteomes:UP000053260}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RV15 {ECO:0000313|EMBL:KUO19888.1,
RC ECO:0000313|Proteomes:UP000053260};
RA Ruckert C., Abdelmohsen U.R., Winkler A., Hentschel U., Kalinowski J.,
RA Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces sp. RV15, isolated from a marine
RT sponge.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:190135;
CC Evidence={ECO:0000256|ARBA:ARBA00034078};
CC -!- SIMILARITY: Belongs to the complex I 24 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00010643}.
CC -!- SIMILARITY: Belongs to the complex I 51 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00007523}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUO19888.1}.
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DR EMBL; LMXB01000047; KUO19888.1; -; Genomic_DNA.
DR RefSeq; WP_067021979.1; NZ_KQ949083.1.
DR AlphaFoldDB; A0A101UZV6; -.
DR STRING; 909626.AQJ91_17195; -.
DR OrthoDB; 9805533at2; -.
DR Proteomes; UP000053260; Unassembled WGS sequence.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR Gene3D; 3.10.20.600; -; 1.
DR Gene3D; 6.10.250.1450; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 1.10.10.1590; NADH-quinone oxidoreductase subunit E; 1.
DR Gene3D; 3.40.50.11540; NADH-ubiquinone oxidoreductase 51kDa subunit; 1.
DR Gene3D; 1.20.1440.230; NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain; 1.
DR InterPro; IPR001949; NADH-UbQ_OxRdtase_51kDa_CS.
DR InterPro; IPR011538; Nuo51_FMN-bd.
DR InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR InterPro; IPR002023; NuoE-like.
DR InterPro; IPR041921; NuoE_N.
DR InterPro; IPR019575; Nuop51_4Fe4S-bd.
DR InterPro; IPR037207; Nuop51_4Fe4S-bd_sf.
DR InterPro; IPR019554; Soluble_ligand-bd.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43578; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR PANTHER; PTHR43578:SF3; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR Pfam; PF01257; 2Fe-2S_thioredx; 1.
DR Pfam; PF01512; Complex1_51K; 1.
DR Pfam; PF10589; NADH_4Fe-4S; 1.
DR Pfam; PF10531; SLBB; 1.
DR SMART; SM00928; NADH_4Fe-4S; 1.
DR SUPFAM; SSF142019; Nqo1 FMN-binding domain-like; 1.
DR SUPFAM; SSF142984; Nqo1 middle domain-like; 1.
DR SUPFAM; SSF140490; Nqo1C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS01099; COMPLEX1_24K; 1.
DR PROSITE; PS00645; COMPLEX1_51K_2; 1.
PE 3: Inferred from homology;
KW 2Fe-2S {ECO:0000256|ARBA:ARBA00022714};
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000053260};
KW Translocase {ECO:0000256|ARBA:ARBA00022967}.
FT DOMAIN 523..570
FT /note="NADH-ubiquinone oxidoreductase 51kDa subunit iron-
FT sulphur binding"
FT /evidence="ECO:0000259|SMART:SM00928"
SQ SEQUENCE 607 AA; 64134 MW; E27AAC4F4646BDA0 CRC64;
MDLHFGDSKP TDDERAAVDA LLGPPESSWE GADRSDADLR WARGGRAARD RRDLLLPGLH
ALNDRVGWIS EGALDYLCRR LTVPPAEAYG VATFYAMFSV KPRPANVLHV CTDLACAAAG
ASELCAGIEA KLGLGSGVSV ERSPCLGLCE RAPAALAVKA GDPVRTAVSA PATVRDAVLA
ASAPDSAPEE PPAAMAVPQA GDPSLALLRR VGVVDPASLD DYRAHGGYTA LRRAFELGPA
GVIREVTDSG LVGRGGAAFP TGRKWQATAS QPDHPHYLVC NADESEPGTF KDRVIMEGDP
YALVEAMTIA AYAIGAHTGY IYLRGEYPRA IHRMQYAVDQ ARARGLLGDD VLGQGYAFDI
EIRRGAGAYI CGEETALFNS IEGYRGEPRS KPPFPVEKGL FGKPTVENNV ETLVNVLPIL
TMGAPAYAAI GTGRSTGPKL FCVSGSVERP GTYELPFGAT LGELLELAGV RDGLRAVLLG
GAAGGFVRPD ETHIPLTFEG TREAGTTLGS GVVMAFDDTV PLPRLLLRIA KFFRDESCGQ
CVPCRVGTVR QEEALHRIAE RTGAAAADDI ALLREVGRAM RDASICGLGQ TAWNAVESAI
DRLGAYE
//
