ID A0A101V0B0_9ACTN Unreviewed; 406 AA.
AC A0A101V0B0;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Beta-ketoacyl synthase {ECO:0000313|EMBL:KUO20114.1};
GN ORFNames=AQJ91_16125 {ECO:0000313|EMBL:KUO20114.1};
OS Streptomyces dysideae.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=909626 {ECO:0000313|EMBL:KUO20114.1, ECO:0000313|Proteomes:UP000053260};
RN [1] {ECO:0000313|EMBL:KUO20114.1, ECO:0000313|Proteomes:UP000053260}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RV15 {ECO:0000313|EMBL:KUO20114.1,
RC ECO:0000313|Proteomes:UP000053260};
RA Ruckert C., Abdelmohsen U.R., Winkler A., Hentschel U., Kalinowski J.,
RA Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces sp. RV15, isolated from a marine
RT sponge.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUO20114.1}.
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DR EMBL; LMXB01000042; KUO20114.1; -; Genomic_DNA.
DR RefSeq; WP_067021572.1; NZ_KQ949082.1.
DR AlphaFoldDB; A0A101V0B0; -.
DR STRING; 909626.AQJ91_16125; -.
DR OrthoDB; 416758at2; -.
DR Proteomes; UP000053260; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:UniProt.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd00832; CLF; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR001969; Aspartic_peptidase_AS.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF322; POLYKETIDE BETA-KETOACYL SYNTHASE 2-RELATED; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00141; ASP_PROTEASE; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000053260};
KW Transferase {ECO:0000256|RuleBase:RU003694}.
FT DOMAIN 4..406
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 406 AA; 41555 MW; 8A659C8217C57134 CRC64;
MSAPTAPVIT GLGICAPTGI GVEAHWSSVL AGKSGIARIE RFDPATYPVR HAGQVPGFTA
AENVPSRLIA QTDHWTHLAL AAGEAALADS GADLTAVPEY EMAVVTSSSS GGTEFGQKEM
TALYRNEPSW VGAYQSIAWF YAATTGQLSI RHKMRGPCGV LACEQAGGLD AIGQARRLVR
RGSRLVVTGG TDASLCPYGL TAQLSTGRLS TVQDPERAYL PFDAEASGHL PGEGGAILVL
ESAEAAGERG AGTGYGRVLG YAAGFDPAPG SGRPRALRRT AEQALADAGL APSDIDVVFA
DGSGVPTDDR DEADAITAVF GPGGVPVTAP KTLTGRLYGG GAPLDVATAL LALREGVIPH
TAHIRDLAPG LGIDLVTGAP RELPLRHALV LARGHGGFTS ALVMGR
//
