ID A0A101VCC8_9SPHN Unreviewed; 722 AA.
AC A0A101VCC8;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=EAL domain-containing protein {ECO:0000259|PROSITE:PS50883};
GN ORFNames=APF78_08120 {ECO:0000313|EMBL:KUO51898.1};
OS Sphingomonadales bacterium BRH_c3.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales.
OX NCBI_TaxID=1734408 {ECO:0000313|EMBL:KUO51898.1, ECO:0000313|Proteomes:UP000061825};
RN [1] {ECO:0000313|EMBL:KUO51898.1, ECO:0000313|Proteomes:UP000061825}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BRH_c3 {ECO:0000313|EMBL:KUO51898.1};
RA Bagnoud A., Chourey K., Hettich R.L., De Bruijn I., Andersson A.F.,
RA Leupin O.X., Schwyn B., Bernier-Latmani R.;
RT "Microbial metabolic network in the subsurface.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUO51898.1}.
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DR EMBL; LOET01000130; KUO51898.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A101VCC8; -.
DR Proteomes; UP000061825; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd13704; PBP2_HisK; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00497; SBP_bac_3; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00062; PBPb; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR PROSITE; PS50883; EAL; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 252..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 447..702
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 722 AA; 80209 MW; EFAEE7DB1187597A CRC64;
MWIALFGGLA QAAAAAEPRV VVFGGDLDYP PYEWLENGKP KGFLIDIEDA IARAGKADAN
HKQAPWPETM AALKSEAVDI VPMFRSDERE KNFWFSRPVF YAHHAIFTKS DPGRVTDLSA
LRLWRVAVEK SSFAHDQIVA GHPVGELVLA SNTNDALGLL ADGRADYAVL ADQPSVRLIS
KLRMPVSKVG TPFWPREYSF AVRRDRPELI AWVDRNLDEV ITSGEFQRIQ AEWQAELDNP
LPAVPLWLVK GWAPFAALVI GAFGILIFVL LRVRSGLVKE RDRRDAAERD ASFLVEHDRA
TGLPRRSKFE TDANSLLKSS GGDRLKLVVL RTEDVRRGEN KLSSEEFSIA QSLVGESLRD
LALLSGYLCD KRFAAVISAG TTHGIVETIG RTLHHAGYEI ELAWGGARFP EHGRDTHDLL
KRAELALSAC SASGRRWAVF DFAMESSLEA DRLVRDFLAF GKDDVFAVYQ PQLDLESGRI
TGAEALARWN HRELGPIAPD EFIPRLEKVG LLGQLTVRMI DEAIKESVRF RAKGFPIKVS
VNVSAQDFAD RDLPDLIDIR LRELGARPED LTVELTESGV VTDPDLVRST LAKLHRIGVR
AAIDDFGTGF ASLASFTELP FQELKIDRLF IERMRDSLSH REAVGSAINL ARRMKMEVVA
EGAPDLATIQ LLKRMRCTRV QSFAISPPLL PDELISFLRE FGLKDIFGGP RADRLKLVGG
LA
//
