ID A0A101VM92_9PROT Unreviewed; 386 AA.
AC A0A101VM92;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein {ECO:0000259|Pfam:PF16576};
GN ORFNames=APF80_00225 {ECO:0000313|EMBL:KUO57354.1};
OS Alphaproteobacteria bacterium BRH_c36.
OC Bacteria; Pseudomonadota; Alphaproteobacteria.
OX NCBI_TaxID=1734406 {ECO:0000313|EMBL:KUO57354.1, ECO:0000313|Proteomes:UP000053382};
RN [1] {ECO:0000313|EMBL:KUO57354.1, ECO:0000313|Proteomes:UP000053382}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BRH_c36 {ECO:0000313|EMBL:KUO57354.1};
RA Bagnoud A., Chourey K., Hettich R.L., De Bruijn I., Andersson A.F.,
RA Leupin O.X., Schwyn B., Bernier-Latmani R.;
RT "Microbial metabolic network in the subsurface.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUO57354.1}.
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DR EMBL; LOEV01000147; KUO57354.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A101VM92; -.
DR STRING; 1734406.APF80_00225; -.
DR Proteomes; UP000053382; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30158; ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER; 1.
DR PANTHER; PTHR30158:SF3; MULTIDRUG EFFLUX PUMP SUBUNIT ACRA-RELATED; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..386
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007109195"
FT DOMAIN 55..282
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 358..386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 143..170
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 386 AA; 41138 MW; BBB5E15D606913B2 CRC64;
MPRRSRQFGN GTLVLLASCL IAACDQGPPK NPPAPPPASV VVAPVSLEDL SSERSFTGRI
EATDKVQIRA RVQGFLKSRL FEEGAKVEAG ELLYEIEPEP FELAVQQAEA NVASAAAAET
FAQQTFERTE ELVRRNTSSR ASLDEAQSAL AQAQATLKAR KAELQTAQLN LSYTKITAPI
SGRAGRSEYS VGNLVGPESD PLVLLVSQDP VYANFPVPQW LLVQVRKAGQ GPESVYVELR
LADGSEYEHT GSVVFTDVQA TTGTDSVLVR AKFPNPEGLL VDQQLVNVQV IRKKPEKKLV
ISQSALLLDQ QGAYALVVDD ANKVQIKRIT VGVQRGPLIV VESGLEAGDR VIVSGHQKAR
PGAEVAPQMA DSASGGLAKA AGATSP
//
