ID   A0A101VQ79_9FIRM        Unreviewed;       621 AA.
AC   A0A101VQ79;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   RecName: Full=Histidine kinase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=APF84_09415 {ECO:0000313|EMBL:KUO58678.1};
OS   Gracilibacter sp. BRH_c7a.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Gracilibacteraceae;
OC   Gracilibacter.
OX   NCBI_TaxID=1734398 {ECO:0000313|EMBL:KUO58678.1, ECO:0000313|Proteomes:UP000053404};
RN   [1] {ECO:0000313|EMBL:KUO58678.1, ECO:0000313|Proteomes:UP000053404}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BRH_c7a {ECO:0000313|EMBL:KUO58678.1};
RA   Bagnoud A., Chourey K., Hettich R.L., De Bruijn I., Andersson A.F.,
RA   Leupin O.X., Schwyn B., Bernier-Latmani R.;
RT   "Microbial metabolic network in the subsurface.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUO58678.1}.
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DR   EMBL; LOEZ01000085; KUO58678.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A101VQ79; -.
DR   STRING; 1734398.APF84_09415; -.
DR   Proteomes; UP000053404; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR011623; 7TMR_DISM_rcpt_extracell_dom1.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR   PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR   PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR   Pfam; PF07695; 7TMR-DISM_7TM; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF06580; His_kinase; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        214..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        240..263
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        269..292
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        304..328
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        334..354
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        361..381
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        393..410
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          214..410
FT                   /note="7TM-DISM receptor extracellular"
FT                   /evidence="ECO:0000259|Pfam:PF07695"
FT   DOMAIN          423..503
FT                   /note="Signal transduction histidine kinase internal
FT                   region"
FT                   /evidence="ECO:0000259|Pfam:PF06580"
FT   DOMAIN          520..618
FT                   /note="Histidine kinase/HSP90-like ATPase"
FT                   /evidence="ECO:0000259|Pfam:PF02518"
SQ   SEQUENCE   621 AA;  71425 MW;  68D0EBD0A9A74A1D CRC64;
     MANRHDYKII LTTAIIILIF IVLVLISVLD SKPPFKPQAN KGILNLSQND FKEYGNLKLD
     GEWEFYWNKL ISYQDPLSQT PDLYADIPDT WNEYSLHGER LSGEGYATYR LHVVTDLAPE
     TTLGLRIYTL SSAYNIFINE KKVASRGKVS ANPAEETGEY GPQAIFFSIP DSEFDMIVHV
     SNHQYARGGF WYGMFLGYPE QIMSLHEALI TKEFFLIGAL LMISLFFFAV YFLRKELRYT
     LIFAFLCLWV SLLVDMVGQF VLLKLFPSLS FNTVILFWYS STEWVLFFLI WYVHELYPSK
     FSRLVLKVSL IYACISQLLF VLTPPLYYTR SGQITNYLDI VLVLCSIIIV GIGIKKNQSG
     GWLNILSMMV VLVTYIHDIG YWTNIIRTPF GEIFYFGLFL FLFIQLVIQA QRIKLFHEQK
     TAAELQFLQA QIKPHFLYNA LNTVISISRY DIEQSRILLA DFSKYLRRSF DFEDLSQFVP
     LRHEIELAQA YTAIEKARFE ERLEVVFNIP DNLEIRVPVL ILQPLIENAV IHGILPKSEG
     GKIQVSITEK ENGYVFTVKD NGVGMNPIIL SLKKDSELKK SVGLHNIDKR LKNIFGSGLE
     ITSTPEVGTQ ISWFVPKATI L
//